Extracts from the History and Medical Properties of Garlic

Overview

Journal Pharmacogn Rev

Date 2012 Jan 10

PMID 22228949

Citations 47

Authors

Biljana Bauer Petrovska

Svetlana Cekovska

Affiliations

Soon will be listed here.

Abstract

At the time when antibiotics and other pharmacy products did not exist, a bulb of garlic itself represented a whole pharmacy industry due to the broad spectrum of effects. Most different suppositions involving this herb are mentioned; some of them were so pointless that they disappeared in time, but some of them have remained until the present days. The garlic was given different names that are still in use such as 'Russian penicillin', 'natural antibiotic', 'vegetable viagra', 'plant talisman', 'rustic's theriac', 'snake grass' etc. Presentation of the development of ideas associated with garlic and the evolution of the notions increased the ability of the pharmacists and physicians to respond to the challenges of their professional services in facilitating human life.

Citing Articles

Garlic-Derived Quorum Sensing Inhibitors: A Novel Strategy Against Fungal Resistance.

Li N, Zhang J, Yu F, Ye F, Tan W, Hao L Drug Des Devel Ther. 2025; 18:6413-6426.

PMID: 39749188 PMC: 11693938. DOI: 10.2147/DDDT.S503302.

Comparative content analysis and biological activity studies of fatty and essential oils from some garlic products sold in Turkish community pharmacies, natural, and fermented garlic.

Ulutas Deniz E, Yuca H, Aydin B, Ozturk G, Coban F, Goger G Food Sci Nutr. 2024; 12(9):6849-6863.

PMID: 39554327 PMC: 11561802. DOI: 10.1002/fsn3.4352.

Alliaceae versus Brassicaceae for Dyslipidemia: State of the Art and Future Perspectives. Systematic Review and Meta-Analysis of Clinical Studies.

Piragine E, Malanima M, Ceccanti C, Guidi L, Martelli A, Lucenteforte E Phytother Res. 2024; 38(12):5765-5781.

PMID: 39343737 PMC: 11634823. DOI: 10.1002/ptr.8350.

Biophysical evidence that frostbite is triggered on nanocrystals of biogenic magnetite in garlic cloves (Allium sativum).

Kobayashi A, Tanaka D, Hidaka H, Sakurai K, Kawai K, Kato T Commun Biol. 2024; 7(1):1167.

PMID: 39289530 PMC: 11408717. DOI: 10.1038/s42003-024-06749-7.

Garlic and Hypertension: Efficacy, Mechanism of Action, and Clinical Implications.

Sleiman C, Daou R, Al Hazzouri A, Hamdan Z, Ghadieh H, Harbieh B Nutrients. 2024; 16(17).

PMID: 39275211 PMC: 11397061. DOI: 10.3390/nu16172895.

References

Dhawan V, Jain S . Garlic supplementation prevents oxidative DNA damage in essential hypertension. Mol Cell Biochem. 2005; 275(1-2):85-94. DOI: 10.1007/s11010-005-0824-2. View

Agarwal K . Therapeutic actions of garlic constituents. Med Res Rev. 1996; 16(1):111-24. DOI: 10.1002/(SICI)1098-1128(199601)16:1<111::AID-MED4>3.0.CO;2-5. View

Isaacsohn J, Moser M, Stein E, Dudley K, Davey J, Liskov E . Garlic powder and plasma lipids and lipoproteins: a multicenter, randomized, placebo-controlled trial. Arch Intern Med. 1998; 158(11):1189-94. DOI: 10.1001/archinte.158.11.1189. View

Zhang Y, Yao H, Huang F, Wu W, Gao Y, Chen Z . Allicin, a major component of garlic, inhibits apoptosis in vital organs in rats with trauma/hemorrhagic shock. Crit Care Med. 2008; 36(12):3226-32. DOI: 10.1097/CCM.0b013e31818f2103. View

Borek C . Garlic reduces dementia and heart-disease risk. J Nutr. 2006; 136(3 Suppl):810S-812S. DOI: 10.1093/jn/136.3.810S. View

Reinhart K, Coleman C, Teevan C, Vachhani P, White C . Effects of garlic on blood pressure in patients with and without systolic hypertension: a meta-analysis. Ann Pharmacother. 2008; 42(12):1766-71. DOI: 10.1345/aph.1L319. View

Silagy C, Neil A . Garlic as a lipid lowering agent--a meta-analysis. J R Coll Physicians Lond. 1994; 28(1):39-45. PMC: 5400934. View

Sovova M, Sova P . [Pharmaceutical importance of Allium sativum L. 5. Hypolipemic effects in vitro and in vivo]. Ceska Slov Farm. 2004; 53(3):117-23. View

Hassan H . Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy. Leuk Res. 2004; 28(7):667-71. DOI: 10.1016/j.leukres.2003.10.008. View

10.

Durak I, Ozturk H, Olcay E, Guven C . Effects of garlic extract supplementation on blood lipid and antioxidant parameters and atherosclerotic plaque formation process in cholesterol-fed rabbits. J Herb Pharmacother. 2004; 2(2):19-32. View

11.

Durak I, Kavutcu M, Aytac B, Avci A, Devrim E, Ozbek H . Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol. J Nutr Biochem. 2004; 15(6):373-7. DOI: 10.1016/j.jnutbio.2004.01.005. View

12.

Borek C . Antioxidant health effects of aged garlic extract. J Nutr. 2001; 131(3s):1010S-5S. DOI: 10.1093/jn/131.3.1010S. View

13.

Amagase H, Petesch B, Matsuura H, Kasuga S, Itakura Y . Intake of garlic and its bioactive components. J Nutr. 2001; 131(3s):955S-62S. DOI: 10.1093/jn/131.3.955S. View

14.

Ichikawa M, Ryu K, Yoshida J, Ide N, Kodera Y, Sasaoka T . Identification of six phenylpropanoids from garlic skin as major antioxidants. J Agric Food Chem. 2003; 51(25):7313-7. DOI: 10.1021/jf034791a. View

15.

Superko H, Krauss R . Garlic powder, effect on plasma lipids, postprandial lipemia, low-density lipoprotein particle size, high-density lipoprotein subclass distribution and lipoprotein(a). J Am Coll Cardiol. 2000; 35(2):321-6. DOI: 10.1016/s0735-1097(99)90541-7. View

16.

Tedeschi P, Maietti A, Boggian M, Vecchiati G, Brandolini V . Fungitoxicity of lyophilized and spray-dried garlic extracts. J Environ Sci Health B. 2007; 42(7):795-9. DOI: 10.1080/03601230701551459. View