Nodal Stations and Diagnostic Performances of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Patients with Non-small Cell Lung Cancer

Overview

Journal J Korean Med Sci

Specialty General Medicine

Date 2012 Jan 6

PMID 22219613

Citations 12

Authors

Byung Woo Jhun

Hye Yun Park

Kyeongman Jeon

Won-Jung Koh

Gee Young Suh

Man Pyo Chung

Hojoong Kim

O Jung Kwon

Joungho Han

Sang-Won Um

Affiliations

Soon will be listed here.

Abstract

There are no accurate data on the relationship between nodal station and diagnostic performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). We evaluated the impact of nodal station and size on the diagnostic performance of EBUS-TBNA in patients with non-small cell lung cancer (NSCLC). Consecutive patients who underwent EBUS-TBNA of mediastinal or hilar lymph nodes for staging or diagnosis of NSCLC were included in this retrospective study. Between May 2009 and February 2010, EBUS-TBNA was performed in 373 mediastinal and hilar lymph nodes in 151 patients. The overall diagnostic sensitivity, specificity, accuracy and negative predictive value (NPV) of EBUS-TBNA were 91.6%, 98.6%, 93.8%, and 84.3%, respectively. NPV of the left side nodal group was significantly lower than those of the other groups (P = 0.047) and sensitivity of the left side nodal group tended to decrease (P = 0.096) compared with those of the other groups. Diagnostic sensitivity and NPV of 4L lymph node were 83.3% and 66.7%, respectively. However, diagnostic performances of EBUS-TBNA did not differ according to nodal size. Bronchoscopists should consider the impact of nodal stations on diagnostic performances of EBUS-TBNA.

Citing Articles

Clinical utility of EBUS-TBNA of hilar, interlobar, and lobar lymph nodes in patients with primary lung cancer.

Wi S, Kim B, Shin S, Jhun B, Yoo H, Jeong B Thorac Cancer. 2022; 13(17):2507-2514.

PMID: 35859356 PMC: 9436691. DOI: 10.1111/1759-7714.14587.

Mediastinal Nodal Staging Performance of Combined Endobronchial and Esophageal Endosonography in Lung Cancer Cases: A Systematic Review and Meta-Analysis.

Liu X, Yang K, Guo W, Ye M, Liu S Front Surg. 2022; 9:890993.

PMID: 35677749 PMC: 9168235. DOI: 10.3389/fsurg.2022.890993.

Crown-Cut Endobronchial Ultrasound Guided Transbronchial Aspiration Needle: First Real-World Experiences.

Oezkan F, Byun W, Loeffler C, Siebolts U, Diessel L, Lambrecht N J Clin Med. 2022; 11(1).

PMID: 35011904 PMC: 8745307. DOI: 10.3390/jcm11010163.

Clinical validity of 25-gauge endobronchial ultrasound-guided transbronchial needle in lymph node staging of lung cancer.

Okubo Y, Matsumoto Y, Tanaka M, Imabayashi T, Uezono Y, Watanabe S J Thorac Dis. 2021; 13(5):3033-3041.

PMID: 34164194 PMC: 8182540. DOI: 10.21037/jtd-20-3383.

Endobronchial ultrasound-guided transbronchial fine needle aspiration: Determinants of adequacy.

Ece D, Keser S, Caglayan B, Salepci B, Babur Guler G, Sensu S Turk Gogus Kalp Damar Cerrahisi Derg. 2020; 26(1):123-131.

PMID: 32082721 PMC: 7018103. DOI: 10.5606/tgkdc.dergisi.2018.14197.

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