Zero Mortality in More Than 300 Hepatic Resections: Validity of Preoperative Volumetric Analysis

Overview

Journal Surg Today

Specialty General Surgery

Date 2011 Dec 28

PMID 22200757

Citations 21

Authors

Shinji Itoh

Ken Shirabe

Akinobu Taketomi

Kazutoyo Morita

Norifumi Harimoto

Eiji Tsujita

Keishi Sugimachi

Yo-Ichi Yamashita

Tomonobu Gion

Yoshihiko Maehara

Affiliations

Soon will be listed here.

Abstract

Purpose: We reviewed a series of patients who underwent hepatic resection at our institution, to investigate the risk factors for postoperative complications after hepatic resection of liver tumors and for procurement of living donor liver transplantation (LDLT) grafts.

Methods: Between April 2004 and August 2007, we performed 304 hepatic resections for liver tumors or to procure grafts for LDLT. Preoperative volumetric analysis was done using 3-dimensional computed tomography (3D-CT) prior to major hepatic resection. We compared the clinicopathological factors between patients with and without postoperative complications.

Results: There was no operative mortality. According to the 3D-CT volumetry, the mean error ratio between the actual and the estimated remnant liver volume was 13.4%. Postoperative complications developed in 96 (31.6%) patients. According to logistic regression analysis, histological liver cirrhosis and intraoperative blood loss >850 mL were significant risk factors of postoperative complications after hepatic resection.

Conclusions: Meticulous preoperative evaluation based on volumetric analysis, together with sophisticated surgical techniques, achieved zero mortality and minimized intraoperative blood loss, which was classified as one of the most significant predictors of postoperative complications after major hepatic resection.

Citing Articles

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Impact of TP53-induced glycolysis and apoptosis regulator on malignant activity and resistance to ferroptosis in intrahepatic cholangiocarcinoma.

Toshida K, Itoh S, Iseda N, Izumi T, Yoshiya S, Toshima T Cancer Sci. 2023; 115(1):170-183.

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Tomiyama T, Itoh S, Iseda N, Toshida K, Kosai-Fujimoto Y, Tomino T Ann Surg Oncol. 2023; 30(6):3378-3389.

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Association between Sarcopenia and Omega-3 Polyunsaturated Fatty Acid in Patients with Hepatocellular Carcinoma.

Itoh S, Nagao Y, Morita K, Kurihara T, Tomino T, Kosai-Fujimoto Y JMA J. 2022; 5(2):169-176.

PMID: 35611230 PMC: 9090533. DOI: 10.31662/jmaj.2022-0037.

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