Efficacy Against Ovine Enzootic Abortion of an Experimental Vaccine Containing Purified Elementary Bodies of Chlamydia Psittaci

Overview

Journal Vet Microbiol

Specialties Microbiology
Veterinary Medicine

Date 1990 Jul 1

PMID 2219662

Citations 8

Authors

I E Anderson

T W Tan

G E Jones

A J Herring

Affiliations

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Abstract

A vaccine prepared from purified, inactivated elementary bodies of Chlamydia psittaci protected sheep against abortion after subcutaneous challenge with live chlamydiae. Immunoblot analysis of serum samples revealed a consistently dominant antibody response against the chlamydial major outer membrane protein in all vaccinated sheep. Reactions to other chlamydial antigens were also detected but were less pronounced or inconsistent. Serological responses detected by complement fixation were variable and did not correlate with immunity.

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Evaluation of the Efficacy of a New Commercially Available Inactivated Vaccine Against Ovine Enzootic Abortion.

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Serological diagnosis of ovine enzootic abortion by enzyme-linked immunosorbent assay with a recombinant protein fragment of the polymorphic outer membrane protein POMP90 of Chlamydophila abortus.

Longbottom D, Fairley S, Chapman S, Psarrou E, Vretou E, Livingstone M J Clin Microbiol. 2002; 40(11):4235-43.

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