Stem Cells for Augmenting Tendon Repair

Overview

Journal Stem Cells Int

Publisher Wiley

Specialty Cell Biology

Date 2011 Dec 23

PMID 22190960

Citations 16

Authors

Lawrence V Gulotta

Salma Chaudhury

Daniel Wiznia

Affiliations

Soon will be listed here.

Abstract

Tendon healing is fraught with complications such as reruptures and adhesion formation due to the formation of scar tissue at the injury site as opposed to the regeneration of native tissue. Stem cells are an attractive option in developing cell-based therapies to improve tendon healing. However, several questions remain to be answered before stem cells can be used clinically. Specifically, the type of stem cell, the amount of cells, and the proper combination of growth factors or mechanical stimuli to induce differentiation all remain to be seen. This paper outlines the current literature on the use of stem cells for tendon augmentation.

Citing Articles

The current status of various preclinical therapeutic approaches for tendon repair.

Liang W, Zhou C, Deng Y, Fu L, Zhao J, Long H Ann Med. 2024; 56(1):2337871.

PMID: 38738394 PMC: 11095292. DOI: 10.1080/07853890.2024.2337871.

Applications of functionally-adapted hydrogels in tendon repair.

Hu J, Liu S, Fan C Front Bioeng Biotechnol. 2023; 11:1135090.

PMID: 36815891 PMC: 9934866. DOI: 10.3389/fbioe.2023.1135090.

Tendon and multiomics: advantages, advances, and opportunities.

Sarmiento P, Little D NPJ Regen Med. 2021; 6(1):61.

PMID: 34599188 PMC: 8486786. DOI: 10.1038/s41536-021-00168-6.

Autograft Long Head Biceps Tendon Can Be Used as a Scaffold for Biologically Augmenting Rotator Cuff Repairs.

Colbath G, Murray A, Siatkowski S, Pate T, Krussig M, Pill S Arthroscopy. 2021; 38(1):38-48.

PMID: 34126215 PMC: 8665938. DOI: 10.1016/j.arthro.2021.05.064.

Does the Use of Injectable Atelocollagen during Arthroscopic Rotator Cuff Repair Improve Clinical and Structural Outcomes?.

Kim I, Kim E, Lim K, Heo K Clin Shoulder Elb. 2020; 22(4):183-189.

PMID: 33330217 PMC: 7714314. DOI: 10.5397/cise.2019.22.4.183.

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