Percutaneous Transluminal Pulmonary Angioplasty Markedly Improves Pulmonary Hemodynamics and Long-term Prognosis in Patients with Chronic Thromboembolic Pulmonary Hypertension

Overview

Journal Circ J

Specialty Cardiology & Vascular Diseases

Date 2011 Dec 22

PMID 22185711

Citations 97

Authors

Koichiro Sugimura

Yoshihiro Fukumoto

Kimio Satoh

Kotaro Nochioka

Yutaka Miura

Tatsuo Aoki

Shunsuke Tatebe

Saori Miyamichi-Yamamoto

Hiroaki Shimokawa

Affiliations

Soon will be listed here.

Abstract

Background: Distal-type chronic thromboembolic pulmonary hypertension (CTEPH) is a fatal disease for which a new therapeutic strategy needs to be developed. We examined the effects of percutaneous transluminal pulmonary angioplasty (PTPA).

Methods And Results: We prospectively enrolled 12 patients with distal-type CTEPH. After stabilizing their condition with pulmonary vasodilators, we then performed PTPA, which markedly improved pulmonary hemodynamics and pulmonary artery structure, as confirmed by angiography and optical coherence tomography, and also significantly improved their long-term prognosis compared with 39 historical controls.

Conclusions: PTPA is a promising therapeutic option for distal-type CTEPH.

Citing Articles

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