Vitamin D Supplementation Does Not Increase Immunogenicity of Seasonal Influenza Vaccine in HIV-infected Adults

Overview

Journal HIV Clin Trials

Specialties Infectious Diseases
Pharmacology

Date 2011 Dec 20

PMID 22180525

Citations 19

Authors

Curtis Cooper

Anona Thorne

Affiliations

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Abstract

The influence of vitamin D on influenza vaccine immunogenicity in HIV was assessed using data from a phase 3, randomized trial conducted during the 2008-2009 influ-enza season. Thirty-three percent of participants were on supplemental vitamin D at baseline. Neither seroconversion nor seroprotection were predicted by vitamin D use for any of the 3 vaccine strains. There is no evidence of improved influenza vaccine immunogenicity with vitamin D supplementation in this HIV-positive population.

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