Therapeutic Consequences of Crystals in the Synovial Fluid: a Review for Clinicians

Overview

Journal Clin Exp Rheumatol

Specialty Rheumatology

Date 2011 Dec 3

PMID 22133072

Citations 6

Authors

Tim L Jansen

Johannes J Rasker

Affiliations

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Abstract

Many crystals may be found in arthritic joints. Rheumatologists are able to diagnose, with a high degree of probability, which crystals induce arthritis in the individual case. A definite diagnosis supported by polarisation microscopy may provide a firm basis for adequate long-term treatment. Recently new insights in the inflammatory processes induced the development of targeted therapies. We review novel developments in crystal-induced arthritis and gout in particular.

Citing Articles

The Diagnostic and Prognostic Value of Synovial Fluid Analysis in Joint Diseases.

Liu D, Xiao W, Li Y Methods Mol Biol. 2023; 2695:295-308.

PMID: 37450127 DOI: 10.1007/978-1-0716-3346-5_20.

Clinical image.

Jansen T Clin Rheumatol. 2020; 39(7):2235-2236.

PMID: 32314177 DOI: 10.1007/s10067-020-05002-w.

Crystal identification of synovial fluid aspiration by polarized light microscopy. An online test suggesting that our traditional rheumatologic competence needs renewed attention and training.

Berendsen D, Neogi T, Taylor W, Dalbeth N, Jansen T Clin Rheumatol. 2016; 36(3):641-647.

PMID: 27837341 DOI: 10.1007/s10067-016-3461-0.

Gadolinium-enhanced MRI features of acute gouty arthritis on top of chronic gouty involvement in different joints.

Emad Y, Ragab Y, El-Naggar A, El-Shaarawy N, Abd-Allah M, Gamal R Clin Rheumatol. 2015; 34(11):1939-47.

PMID: 25681072 DOI: 10.1007/s10067-015-2895-0.

Additive value for ultrasonographic signal in a screening algorithm for patients presenting with acute mono-/oligoarthritis in whom gout is suspected.

Lamers-Karnebeek F, Van Riel P, Jansen T Clin Rheumatol. 2014; 33(4):555-9.

PMID: 24510062 DOI: 10.1007/s10067-014-2505-6.