Risk Factors for Group B Streptococcus Colonization Among Pregnant Women in Korea

Overview

Journal Epidemiol Health

Specialty Public Health

Date 2011 Nov 24

PMID 22111030

Citations 22

Authors

Eun Ju Kim

Kwan Young Oh

Moon Young Kim

Yong Soo Seo

Jung-Hwan Shin

Young Rae Song

Jae-Hyug Yang

Betsy Foxman

Moran Ki

Affiliations

Soon will be listed here.

Abstract

Objectives: To identify obstetric and maternal factors related to Group B Streptococcus (GBS) colonization in pregnant women in Korea.

Methods: The study was conducted between the years 2006-2008 in four hospitals, Cheil and Eulji hospital in Seoul, and Motae and Eulji hospital in Daejeon. We recruited 2,644 pregnant women between 35 to 37 weeks of gestation who had visited for antenatal care. Participants completed a questionnaire, and urine, vaginal and rectal specimens were obtained and cultured using selective broth media. After delivery, medical records were reviewed.

Results: GBS colonization was significantly associated with hospital, age group, education, frequency of pregnancy, and premature rupture of membranes (PROM, more than 18 hours). After adjustment for other variables, Cheil hospital (odds ratio [OR], 2.05; 95% confidence interval [CI], 1.20-3.52), and the first pregnancy (OR, 2.32; 95% CI, 1.12-4.81) remained significant. History of vaginitis showed marginal significance (OR, 1.50; 95% CI, 0.98-2.29).

Conclusion: To prevent GBS infection of neonates, clinicians should be alert to the potentially higher risk of GBS colonization in pregnant women in their first pregnancy, and women with premature rupture of membranes (PROM) (18 hours+) or who have a history of vaginitis.

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