Using Three Legacy Measures to Develop a Health-related Quality of Life Tool for Young Adult Survivors of Childhood Cancer

Overview

Journal Qual Life Res

Specialties Pharmacology
Rehabilitation Medicine

Date 2011 Nov 22

PMID 22101901

Citations 4

Authors

I-Chan Huang

Gwendolyn P Quinn

Pey-Shan Wen

Elizabeth A Shenkman

Dennis A Revicki

Kevin Krull

Zhushan Li

Patricia D Shearer

Affiliations

Soon will be listed here.

Abstract

Background: Little attention has been paid to selecting and developing health-related quality of life (HRQOL) measurement tools for young adult survivors of childhood cancer (YASCC). The primary purpose of this study was to develop a HRQOL tool for YASCC based on three legacy instruments.

Methods: Data collected from 151 YASCC were analyzed. HRQOL was measured using the Medical Outcomes Study SF-36, Quality of Life in Adult Cancer Survivors, and Quality of Life-Cancer Survivor. We used the following stages to develop our HRQOL tool: mapping items from three instruments into a common HRQOL construct, checking dimensionality using confirmatory factor analyses (CFA), and equating items using Rasch modeling.

Results: We assigned 123 items to a HRQOL construct comprised of six generic and eight survivor-specific domains. CFA retained 107 items that meet the assumptions of unidimensionality and local independence. Rasch analysis retained 68 items that satisfied the indices of information-weighted/outlier-sensitive fit statistic mean square. However, items in most domains possess relatively easy measurement properties, whereas YASCC's underlying HRQOL was on the middle to higher levels.

Conclusions: Psychometric properties of the established tool for measuring HRQOL of YASCC were not satisfied. Future studies need to refine this tool, especially adding more challenging items.

Citing Articles

Application of Rasch Analysis for Development and Psychometric Properties of Adolescents' Quality of Life Instruments: A Systematic Review.

Dabaghi S, Esmaielzadeh F, Rohani C Adolesc Health Med Ther. 2020; 11:173-197.

PMID: 33204203 PMC: 7666979. DOI: 10.2147/AHMT.S265413.

Patterns of unmet needs in adolescent and young adult (AYA) cancer survivors: in their own words.

Wong A, Chang T, Christopher K, Lau S, Beaupin L, Love B J Cancer Surviv. 2017; 11(6):751-764.

PMID: 28357785 DOI: 10.1007/s11764-017-0613-4.

Emotional distress impacts quality of life evaluation: a report from the Childhood Cancer Survivor Study.

Huang I, Brinkman T, Armstrong G, Leisenring W, Robison L, Krull K J Cancer Surviv. 2017; 11(3):309-319.

PMID: 28070769 PMC: 5419851. DOI: 10.1007/s11764-016-0589-5.

The Childhood Cancer Survivor Study-Neurocognitive Questionnaire (CCSS-NCQ) revised: item response analysis and concurrent validity.

Kenzik K, Huang I, Brinkman T, Baughman B, Ness K, Shenkman E Neuropsychology. 2014; 29(1):31-44.

PMID: 24933482 PMC: 4268097. DOI: 10.1037/neu0000095.

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