Beyond Base Pairs to Bedside: a Population Perspective on How Genomics Can Improve Health

Overview

Journal Am J Public Health

Specialty Public Health

Date 2011 Nov 19

PMID 22095352

Citations 24

Authors

Muin J Khoury

Marta Gwinn

M Scott Bowen

W David Dotson

Affiliations

Soon will be listed here.

Abstract

A decade after the sequencing of the human genome, the National Human Genome Research Institute announced a strategic plan for genomic medicine. It calls for evaluating the structure and biology of genomes, understanding the biology of disease, advancing the science of medicine, and improving the effectiveness of health care. Fulfilling the promise of genomics urgently requires a population perspective to complement the bench-to-bedside model of translation. A population approach should assess the contribution of genomics to health in the context of social and environmental determinants of disease; evaluate genomic applications that may improve health care; design strategies for integrating genomics into practice; address ethical, legal, and social issues; and measure the population health impact of new technologies.

Citing Articles

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