Use of Serum Cholesterol/triglyceride Ratio to Discern for Which Individuals the Friedewald Formula Can Be Used Confidently

Overview

Journal Clin Chem

Publisher Oxford University Press

Specialty Biochemistry

Date 1990 Sep 1

PMID 2208709

Citations 4

Authors

M Gonzalez Estrada

C R Rodriguez Ferrer

I R Astarloa

E M Lahera

Affiliations

Soon will be listed here.

Abstract

The values of low-density lipoprotein cholesterol obtained according to the Friedewald formula (Clin Chem 1972; 18:499-502), or by the De Long transformation (J Am Med Assoc 1986;256:2372-7), were compared with the values obtained when the individual cholesterol/triglyceride ratio of very-low-density lipoprotein was used for estimating the contribution of this lipoprotein to the total cholesterol. We found that these formulas gave the greatest errors for individuals with a low serum cholesterol/triglyceride ratio. We propose criteria for deciding when the numerically calculated value of low-density cholesterol is appropriate, and when it is not.

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