Role of Sexual Transmission of HIV Among Young Noninjection and Injection Opiate Users: a Respondent-driven Sampling Study

Overview

Journal Sex Transm Dis

Specialty Infectious Diseases

Date 2011 Nov 16

PMID 22082729

Citations 12

Authors

Jian Li

Hongjie Liu

Jianhua Li

Jian Luo

Don Des Jarlais

Nana Koram

Affiliations

Soon will be listed here.

Abstract

Background: Sexual transmissibility of HIV among young drug users in China has been investigated in few studies. The objective of this study was to examine the role of sexual transmission on HIV infection among injection drug users (IDUs) and noninjection drug users (NIDUs).

Methods: Respondent-driven sampling (RDS) was used to recruit 426 young heroin/opium drug users in Yunnan, China. Logistic regression modeling was performed to examine interrelationships among risky sexual behaviors, drug-use modes, and drug-use practices.

Results: Substantial proportions of NIDUs and IDUs reported engagement in risky sexual behaviors including: (1) multiple sexual partners (42% of NIDUs vs. 37% of IDUs), (2) concurrent sexual partnerships (48% vs. 46%), (3) commercial sex partners (23% vs. 24%), and sex partners who were NIDUs (14% vs. 17%). Both NIDUs and IDUs reported low levels of condom use with nonregular partners (48% vs. 42%) and regular partner (24% vs. 27%), and having a history of recent methamphetamine use (21% vs. 18%). Compared to IDUs, NIDUs reported having had fewer sex partners who were IDUs, fewer IDU network peers, more NIDU network peers, and having lower levels of HIV knowledge and self-perceived HIV risk.

Conclusions: Generalization of the HIV epidemic from high-risk groups to the general population may be driven by risky sexual behavior among drug users. Reducing sexual transmission of HIV among both IDUs and NIDUs is the next major challenge for HIV intervention among drug users in China.

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References

Des Jarlais D, Arasteh K, McKnight C, Perlman D, Hagan H, Semaan S . Gender and age patterns in HSV-2 and HIV infection among non-injecting drug users in New York City. Sex Transm Dis. 2010; 37(10):637-43. PMC: 4455877. DOI: 10.1097/OLQ.0b013e3181e1a64a. View

Strathdee S, Sherman S . The role of sexual transmission of HIV infection among injection and non-injection drug users. J Urban Health. 2004; 80(4 Suppl 3):iii7-14. PMC: 3456264. DOI: 10.1093/jurban/jtg078. View

Mathers B, Degenhardt L, Phillips B, Wiessing L, Hickman M, Strathdee S . Global epidemiology of injecting drug use and HIV among people who inject drugs: a systematic review. Lancet. 2008; 372(9651):1733-45. DOI: 10.1016/S0140-6736(08)61311-2. View

Duan S, Shen S, Bulterys M, Jia Y, Yang Y, Xiang L . Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route. BMC Public Health. 2010; 10:180. PMC: 2858119. DOI: 10.1186/1471-2458-10-180. View

Li J, Ha T, Zhang C, Liu H . The Chinese government's response to drug use and HIV/AIDS: a review of policies and programs. Harm Reduct J. 2010; 7:4. PMC: 2847555. DOI: 10.1186/1477-7517-7-4. View

Des Jarlais D, Arasteh K, Perlis T, Hagan H, Abdul-Quader A, Heckathorn D . Convergence of HIV seroprevalence among injecting and non-injecting drug users in New York City. AIDS. 2007; 21(2):231-5. DOI: 10.1097/QAD.0b013e3280114a15. View

Zhang L, Li J, Lai W, Feng L, Zeng Y, Liu L . Prevalence and correlates of needle-sharing among new and long-term injection drug users in southwest China. Subst Use Misuse. 2010; 45(14):2503-23. DOI: 10.3109/10826084.2010.487234. View

Strathdee S, Stockman J . Epidemiology of HIV among injecting and non-injecting drug users: current trends and implications for interventions. Curr HIV/AIDS Rep. 2010; 7(2):99-106. PMC: 2856849. DOI: 10.1007/s11904-010-0043-7. View

Jenness S, Begier E, Neaigus A, Murrill C, Wendel T, Hagan H . Unprotected anal intercourse and sexually transmitted diseases in high-risk heterosexual women. Am J Public Health. 2010; 101(4):745-50. PMC: 3052332. DOI: 10.2105/AJPH.2009.181883. View

10.

Niccolai L, Shcherbakova I, Toussova O, Kozlov A, Heimer R . The potential for bridging of HIV transmission in the Russian Federation: sex risk behaviors and HIV prevalence among drug users (DUs) and their non-DU sex partners. J Urban Health. 2009; 86 Suppl 1:131-43. PMC: 2705488. DOI: 10.1007/s11524-009-9369-0. View

11.

Li J, Zhang R, Liu H . A preliminary study of methamphetamine use in Yunnan, China. AIDS Patient Care STDS. 2008; 22(7):543-4. DOI: 10.1089/apc.2007.0205. View

12.

Wu Z, Sullivan S, Wang Y, Rotheram-Borus M, Detels R . Evolution of China's response to HIV/AIDS. Lancet. 2007; 369(9562):679-90. PMC: 7137740. DOI: 10.1016/S0140-6736(07)60315-8. View

13.

Liu H, Grusky O, Zhu Y, Li X . Do drug users in China who frequently receive detoxification treatment change their risky drug use practices and sexual behavior?. Drug Alcohol Depend. 2006; 84(1):114-21. DOI: 10.1016/j.drugalcdep.2006.01.004. View

14.

Li J, Liu H, Li J, Luo J, Koram N, Detels R . Sexual transmissibility of HIV among opiate users with concurrent sexual partnerships: an egocentric network study in Yunnan, China. Addiction. 2011; 106(10):1780-7. PMC: 3142291. DOI: 10.1111/j.1360-0443.2011.03459.x. View

15.

Castor D, Pilowsky D, Hadden B, Fuller C, Ompad D, de Leon C . Sexual risk reduction among non-injection drug users: report of a randomized controlled trial. AIDS Care. 2010; 22(1):62-70. DOI: 10.1080/09540120903012510. View

16.

Morris M . Barking up the wrong evidence tree. Comment on Lurie & Rosenthal, "Concurrent partnerships as a driver of the HIV epidemic in sub-Saharan Africa? The evidence is limited". AIDS Behav. 2009; 14(1):31-3. PMC: 2814034. DOI: 10.1007/s10461-009-9639-6. View

17.

Liu H, Grusky O, Li X, Ma E . Drug users: a potentially important bridge population in the transmission of sexually transmitted diseases, including AIDS, in China. Sex Transm Dis. 2006; 33(2):111-7. DOI: 10.1097/01.olq.0000199762.28231.ee. View

18.

Jia M, Luo H, Ma Y, Wang N, Smith K, Mei J . The HIV epidemic in Yunnan Province, China, 1989-2007. J Acquir Immune Defic Syndr. 2010; 53 Suppl 1:S34-40. DOI: 10.1097/QAI.0b013e3181c7d6ff. View

19.

Liu H, Liu H, Cai Y, Rhodes A, Hong F . Money boys, HIV risks, and the associations between norms and safer sex: a respondent-driven sampling study in Shenzhen, China. AIDS Behav. 2008; 13(4):652-62. DOI: 10.1007/s10461-008-9475-0. View

20.

Li X, He G, Wang H, Williams A . Consequences of drug abuse and HIV/AIDS in China: recommendations for integrated care of HIV-infected drug users. AIDS Patient Care STDS. 2009; 23(10):877-84. DOI: 10.1089/apc.2009.0015. View