» Articles » PMID: 22022099

Intraincisional Vs Intraperitoneal Infiltration of Local Anaesthetic for Controlling Early Post-laparoscopic Cholecystectomy Pain

Overview
Specialty Gastroenterology
Date 2011 Oct 25
PMID 22022099
Citations 18
Authors
Affiliations
Soon will be listed here.
Abstract

Background: The study was designed to compare the effect of intraincisional vs intraperitoneal infiltration of levobupivacaine 0.25% on post-operative pain in laparoscopic cholecystectomy.

Materials And Methods: This randomised controlled study was carried out on 189 patients who underwent laparoscopic cholecystectomy. Group 1 was the control group and did not receive either intraperitoneal or intraincisional levobupivacaine. Group 2 was assigned to receive local infiltration (intraincisional) of 20 ml solution of levobupivacaine 0.25%, while Group 3 received 20 ml solution of levobupivacaine 0.25% intraperitoneally. Post-operative pain was recorded for 24 hours post-operatively.

Results: Post-operative abdominal pain was significantly lower with intraincisional infiltration of levobupivacaine 0.25% in group 2. This difference was reported from 30 minutes till 24 hours post-operatively. Right shoulder pain showed significantly lower incidence in group 2 and group 3 compared to control group. Although statistically insignificant, shoulder pain was less in group 3 than group 2.

Conclusion: Intraincisional infiltration of levobupivacaine is more effective than intraperitoneal route in controlling post-operative abdominal pain. It decreases the need for rescue analgesia.

Citing Articles

Liver Bed Infiltration With Isobaric Levobupivacaine Versus Intravenous Paracetamol Analgesia for Postoperative Pain Management in Patients Undergoing Laparoscopic Cholecystectomy.

Dhar S, Kaur A, Panghal R, Mushtaq M, Kaur I, Gupta A Cureus. 2025; 16(12):e76644.

PMID: 39898134 PMC: 11781901. DOI: 10.7759/cureus.76644.


Regional anaesthesia for postoperative pain management following laparoscopic, visceral, non-oncological surgery a systematic review and meta-analysis.

Lohmoller K, Carstensen V, Pogatzki-Zahn E, Freys S, Weibel S, Schnabel A Surg Endosc. 2024; 38(4):1844-1866.

PMID: 38307961 DOI: 10.1007/s00464-023-10667-w.


Single-shot regional anesthesia for laparoscopic cholecystectomies: a systematic review and network meta-analysis.

De Cassai A, Sella N, Geraldini F, Tulgar S, Ahiskalioglu A, Dost B Korean J Anesthesiol. 2022; 76(1):34-46.

PMID: 36345156 PMC: 9902189. DOI: 10.4097/kja.22366.


Evaluation of post laparoscopic cholecystectomy pain after subcutaneous injection of lidocaine at port site versus lidocaine spray on gallbladder bed after cholecystectomy: a randomized controlled trial.

Kiany F, Yazd S, Shahriarirad R, Kamran H, Karoobi M, Shabani Mofrad N Langenbecks Arch Surg. 2022; 407(7):2853-2859.

PMID: 35939102 DOI: 10.1007/s00423-022-02645-y.


Comparison of Trocar Site versus Trocar Site Plus Intraperitoneal Instillation of Local Anesthetic for Shoulder Pain Following Laparoscopic Abdominal Surgery.

Lysander S, Kumar G, Balasubramanian A, Krishnan R, Raghuraman M, Narayanan S Anesth Essays Res. 2022; 15(4):375-378.

PMID: 35422541 PMC: 9004265. DOI: 10.4103/aer.aer_156_21.


References
1.
Bisgaard T . Analgesic treatment after laparoscopic cholecystectomy: a critical assessment of the evidence. Anesthesiology. 2006; 104(4):835-46. DOI: 10.1097/00000542-200604000-00030. View

2.
Lepner U, Goroshina J, Samarutel J . Postoperative pain relief after laparoscopic cholecystectomy: a randomised prospective double-blind clinical trial. Scand J Surg. 2003; 92(2):121-4. View

3.
Cunniffe M, McAnena O, Dar M, Calleary J, Flynn N . A prospective randomized trial of intraoperative bupivacaine irrigation for management of shoulder-tip pain following laparoscopy. Am J Surg. 1998; 176(3):258-61. DOI: 10.1016/s0002-9610(98)00150-0. View

4.
Bisgaard T, Kehlet H, Rosenberg J . Pain and convalescence after laparoscopic cholecystectomy. Eur J Surg. 2001; 167(2):84-96. DOI: 10.1080/110241501750070510. View

5.
Uzunkoy A, Coskun A, Akinci O . The value of pre-emptive analgesia in the treatment of postoperative pain after laparoscopic cholecystectomy. Eur Surg Res. 2001; 33(1):39-41. DOI: 10.1159/000049691. View