Vitamin D and Asthma

Overview

Journal Am J Respir Crit Care Med

Specialty Critical Care

Date 2011 Oct 22

PMID 22016447

Citations 73

Authors

Grace Paul

John M Brehm

John F Alcorn

Fernando Holguin

Shean J Aujla

Juan C Celedon

Affiliations

Soon will be listed here.

Abstract

Vitamin D deficiency and asthma are common conditions that share risk factors such as African American ethnicity, inner-city residence, and obesity. This review provides a critical examination of current experimental and epidemiologic evidence of a causal association between vitamin D status and asthma or asthma morbidity, including potential protective mechanisms such as antiviral effects and enhanced steroid responsiveness. Because most published epidemiologic studies of vitamin D and asthma or asthma morbidity are observational, a recommendation for or against vitamin D supplementation as preventive or secondary treatment for asthma is not advisable and must await results of ongoing clinical trials. Should these trials confirm a beneficial effect of vitamin D, others will be needed to assess the role of vitamin D supplementation to prevent or treat asthma in different groups such as infants, children of school age, and ethnic minorities.

Citing Articles

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Vitamin D Deficiency and Pediatric Obstructive Sleep Apnea Severity.

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