Resolvins and Inflammatory Pain

Overview

Journal F1000 Med Rep

Specialty General Medicine

Date 2011 Oct 18

PMID 22003366

Citations 9

Authors

Claudia Sommer

Frank Birklein

Affiliations

Soon will be listed here.

Abstract

Resolvins are a group of molecules derived from omega-3 fatty acids. They are part of a biochemical program that allows inflamed tissues to return to homeostasis once the need for the inflammatory response is over. Resolvins act in very low dose ranges in vitro and in vivo. New data suggest that they might have the potential to become very potent analgesic drugs in inflammatory pain.

Citing Articles

Effects of Omega-3 Polyunsaturated Fatty Acids on the Formation of Adipokines, Cytokines, and Oxylipins in Retroperitoneal Adipose Tissue of Mice.

Wenderoth T, Feldotto M, Hernandez J, Schaffer J, Leisengang S, Pflieger F Int J Mol Sci. 2024; 25(18).

PMID: 39337391 PMC: 11432517. DOI: 10.3390/ijms25189904.

The role of neuroinflammation in the transition of acute to chronic pain and the opioid-induced hyperalgesia and tolerance.

Echeverria-Villalobos M, Tortorici V, Brito B, Ryskamp D, Uribe A, Weaver T Front Pharmacol. 2024; 14:1297931.

PMID: 38161698 PMC: 10755684. DOI: 10.3389/fphar.2023.1297931.

Omega-3 Lipid Mediators: Modulation of the M1/M2 Macrophage Phenotype and Its Protective Role in Chronic Liver Diseases.

Videla L, Valenzuela R, Del Campo A, Zuniga-Hernandez J Int J Mol Sci. 2023; 24(21).

PMID: 37958514 PMC: 10647594. DOI: 10.3390/ijms242115528.

Complex and Controversial Roles of Eicosanoids in Fungal Pathogenesis.

Mendoza S, Zamith-Miranda D, Takacs T, Gacser A, Nosanchuk J, Guimaraes A J Fungi (Basel). 2021; 7(4).

PMID: 33800694 PMC: 8065571. DOI: 10.3390/jof7040254.

Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice.

Zhang L, Terrando N, Xu Z, Bang S, Jordt S, Maixner W Front Pharmacol. 2018; 9:412.

PMID: 29765320 PMC: 5938385. DOI: 10.3389/fphar.2018.00412.

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