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The Prevalence of Giardia Intestinalis in Dyspeptic and Diabetic Patients

Overview
Journal ISRN Gastroenterol
Specialty Gastroenterology
Date 2011 Oct 13
PMID 21991517
Citations 4
Authors
Gozde Dervis Hakim
Safak Kiziltas
Hilmi Ciftci
Safak Goktas
Ilyas Tuncer
Affiliations
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Abstract

Background and Aims. We aimed to investigate the prevalence of Giardiasis in patients with dyspepsia and patients with diabetes mellitus. Methods. 400 patients and 100 healthy persons were included in this clinical prospective study. The number of patients in each group was equal, 200 dyspeptic and 200 diabetic, respectively. The antigen of G. lntestinalis was determined in the stool specimens by ELISA method. Results. The frequency of Giardiasis was 7% in dyspeptic and 15% in diabetic patients. There was no positive results in any of the healthy persons. There was a significant difference in prevalence rate of Giardiasis between patients with dyspepsia and diabetes mellitus (P < 0.05). Conclusions. These results revealed that the prevalence of Giardiasis in dyspepsia and with diabetes mellitus was high in our country. This is the first study investigating the prevalence of Giardiasis in diabetic patients. To investigate Giardiasis in diabetic patients, who have dyspepsia or not, may be a good approach for public health.

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References
1.
Tack J, Talley N, Camilleri M, Holtmann G, Hu P, Malagelada J . Functional gastroduodenal disorders. Gastroenterology. 2006; 130(5):1466-79. DOI: 10.1053/j.gastro.2005.11.059. View
2.
Musher D, Musher B . Contagious acute gastrointestinal infections. N Engl J Med. 2004; 351(23):2417-27. DOI: 10.1056/NEJMra041837. View
3.
Duque-Beltran S, Nicholls-Orejuela R, Arevalo-Jamaica A, Guerrero-Lozano R, Montenegro S, James M . Detection of Giardia duodenalis antigen in human fecal eluates by enzyme-linked immunosorbent assay using polyclonal antibodies. Mem Inst Oswaldo Cruz. 2003; 97(8):1165-8. DOI: 10.1590/s0074-02762002000800018. View
4.
Carr Jr M, Ma J, Green P . Giardia lamblia in patients undergoing endoscopy: lack of evidence for a role in nonulcer dyspepsia. Gastroenterology. 1988; 95(4):972-4. DOI: 10.1016/0016-5085(88)90171-0. View
5.
Eckmann L, Gillin F . Microbes and microbial toxins: paradigms for microbial-mucosal interactions I. Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogen Giardia lamblia. Am J Physiol Gastrointest Liver Physiol. 2000; 280(1):G1-6. DOI: 10.1152/ajpgi.2001.280.1.G1. View