Hypocalcemic Cardiomyopathy Presenting As Cardiogenic Shock

Overview

Journal Ann Pediatr Cardiol

Specialty Cardiology & Vascular Diseases

Date 2011 Oct 7

PMID 21976876

Citations 11

Authors

Pankaj Gupta

Munesh Tomar

Sitaraman Radhakrishnan

Savitri Shrivastava

Affiliations

Soon will be listed here.

Abstract

Hypocalcemia is a less known but treatable cause for dilated cardiomyopathy, leading to severe heart failure in children. Cardiogenic shock related to hypocalcemic cardiomyopathy is a rare event. We describe 5 infants presenting with cardiogenic shock over 3 years, who were found to have severe hypocalcemia as a sole cause of myocardial dysfunction. The patients responded to calcium and vitamin D supplementation promptly and left ventricular systolic function normalized within months of treatment. In any case of cardiogenic shock, hypocalcemia should be included in the differential diagnosis and must be investigated.

Citing Articles

Serum electrolytes in children with heart failure on diuretic therapy at Jakaya Kikwete Cardiac Institute, Dar es Salaam, Tanzania: a cross-sectional study.

Mushi S, Kalezi Z, Simbila A Pan Afr Med J. 2024; 48:181.

PMID: 39677543 PMC: 11645664. DOI: 10.11604/pamj.2024.48.181.41906.

Severe hypocalcemia as a cause of transient ischemic attack? A debatable case and evidence from literature.

Zufry H, Debbyousha M, Firdausa S, Ekadamayanti A, Sucipto K, Sari J Narra J. 2024; 3(2):e228.

PMID: 38450273 PMC: 10914022. DOI: 10.52225/narra.v3i2.228.

Vitamin D and Its Myriad Disease Associations: Can the Heart be Left Behind?.

Parameswaran N Indian J Crit Care Med. 2023; 27(7):463-464.

PMID: 37502292 PMC: 10369319. DOI: 10.5005/jp-journals-10071-24491.

Clinical Profile, Intensive Care Needs and Outcome of Children with Dilated Cardiomyopathy Associated with Vitamin D Deficiency: A 5-year PICU Experience.

Kumar S, Randhawa M, Angurana S, Nallasamy K, Bansal A, Kumar M Indian J Crit Care Med. 2023; 27(7):510-514.

PMID: 37502290 PMC: 10369324. DOI: 10.5005/jp-journals-10071-24484.

The ABCDE approach to difficult weaning from venoarterial extracorporeal membrane oxygenation.

Meuwese C, Brodie D, Donker D Crit Care. 2022; 26(1):216.

PMID: 35841052 PMC: 9284848. DOI: 10.1186/s13054-022-04089-8.

References

Tomar M, Radhakrishnan S, Shrivastava S . Myocardial dysfunction due to hypocalcemia. Indian Pediatr. 2010; 47(9):781-3. DOI: 10.1007/s13312-010-0117-z. View

Rimailho A, Bouchard P, Schaison G, Richard C, AUZEPY P . Improvement of hypocalcemic cardiomyopathy by correction of serum calcium level. Am Heart J. 1985; 109(3 Pt 1):611-3. DOI: 10.1016/0002-8703(85)90579-4. View

Daubeney P, Nugent A, Chondros P, Carlin J, Colan S, Cheung M . Clinical features and outcomes of childhood dilated cardiomyopathy: results from a national population-based study. Circulation. 2006; 114(24):2671-8. DOI: 10.1161/CIRCULATIONAHA.106.635128. View

Uysal S, Kalayci A, Baysal K . Cardiac functions in children with vitamin D deficiency rickets. Pediatr Cardiol. 1999; 20(4):283-6. DOI: 10.1007/s002469900464. View

Gulati S, Bajpai A, Juneja R, Kabra M, Bagga A, Kalra V . Hypocalcemic heart failure masquerading as dilated cardiomyopathy. Indian J Pediatr. 2001; 68(3):287-90. DOI: 10.1007/BF02723209. View

Price D, Stanford Jr L, Braden D, Ebeid M, Smith J . Hypocalcemic rickets: an unusual cause of dilated cardiomyopathy. Pediatr Cardiol. 2003; 24(5):510-2. DOI: 10.1007/s00246-002-0251-z. View

Brown J, Nunez S, Russell M, Spurney C . Hypocalcemic rickets and dilated cardiomyopathy: case reports and review of literature. Pediatr Cardiol. 2009; 30(6):818-23. DOI: 10.1007/s00246-009-9444-z. View

Ushasree B, Shivani V, Venkateshwari A, Jain R, Narsimhan C, Nallari P . Epidemiology and genetics of dilated cardiomyopathy in the Indian context. Indian J Med Sci. 2009; 63(7):288-96. View

Towbin J, Lowe A, Colan S, Sleeper L, Orav E, Clunie S . Incidence, causes, and outcomes of dilated cardiomyopathy in children. JAMA. 2006; 296(15):1867-76. DOI: 10.1001/jama.296.15.1867. View

10.

Levine S, Rheams C . Hypocalcemic heart failure. Am J Med. 1985; 78(6 Pt 1):1033-5. DOI: 10.1016/0002-9343(85)90228-1. View

11.

Kudoh C, Tanaka S, Marusaki S, Takahashi N, Miyazaki Y, Yoshioka N . Hypocalcemic cardiomyopathy in a patient with idiopathic hypoparathyroidism. Intern Med. 1992; 31(4):561-8. DOI: 10.2169/internalmedicine.31.561. View

12.

Olgun H, Ceviz N, Ozkan B . A case of dilated cardiomyopathy due to nutritional vitamin D deficiency rickets. Turk J Pediatr. 2003; 45(2):152-4. View

13.

Altunbas H, Balci M, Yazicioglu G, Semiz E, Ozbilim G, Karayalcin U . Hypocalcemic cardiomyopathy due to untreated hypoparathyroidism. Horm Res. 2003; 59(4):201-4. DOI: 10.1159/000069324. View

14.

Maiya S, Sullivan I, Allgrove J, Yates R, Malone M, Brain C . Hypocalcaemia and vitamin D deficiency: an important, but preventable, cause of life-threatening infant heart failure. Heart. 2007; 94(5):581-4. DOI: 10.1136/hrt.2007.119792. View