A Novel Degraded Sesquiterpene from the Fresh Stem of Aquilaria Sinensis

Overview

Journal J Asian Nat Prod Res

Publisher Informa Healthcare

Specialties Biology
Chemistry

Date 2011 Oct 7

PMID 21972811

Citations 3

Authors

Ke Peng

Wen-Li Mei

You-Xing Zhao

Le-He Tan

Qing-Huang Wang

Hao-Fu Dai

Affiliations

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Abstract

A novel degraded sesquiterpene, named aquilarin B (1), together with two known compounds (2 and 3), was isolated from the EtOH extract of the fresh stem of Aquilaria sinensis (Lour.) Gilg. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY, HMBC, and ROESY). The cytotoxic activities of the three compounds against three human tumor cell lines K562, SMMC-7721, and SGC-7901 were evaluated, and compound 3 exhibited obvious cytotoxic activity.

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