Implications of Portal Vein Thrombosis After Splenectomy for Patients with Idiopathic Portal Hypertension

Overview

Journal Surg Today

Specialty General Surgery

Date 2011 Oct 5

PMID 21969148

Citations 6

Authors

Teijiro Hirashita

Masayuki Ohta

Seiichiro Kai

Takashi Masuda

Hidetoshi Eguchi

Yukio Iwashita

Tadashi Ogawa

Seigo Kitano

Affiliations

Soon will be listed here.

Abstract

Purpose: Idiopathic portal hypertension (IPH) is considered to be closely related to portal vein thrombosis (PVT). The aim of this study was to clarify the incidence, clinical characteristics, and outcomes of PVT in patients with IPH after splenectomy.

Methods: We investigated the rates, clinical characteristics, and outcomes of PVT in 18 patients who underwent splenectomy for IPH, during a mean follow-up period of 152 ± 83 months.

Results: Seven of the 18 patients (39%) experienced gastrointestinal bleeding, which was from the varices in 4. Eight patients (44%) had PVT, and the mean interval until its detection after splenectomy was 22 ± 41 months. The cumulative gastrointestinal bleeding rates 5, 10, and 15 years after surgery were 24%, 31%, and 41%, respectively. The cumulative survival rates 5, 10, and 15 years after surgery were 94%, 74%, and 65%, respectively. There were no significant differences in the cumulative gastrointestinal bleeding and survival rates between patients with and those without PVT.

Conclusion: Despite the high incidence of PVT in IPH patients postsplenectomy, it may not be related to their gastrointestinal bleeding or prognosis.

Citing Articles

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Predictors of portal and splenic vein thrombosis after laparoscopic splenectomy: a retrospective analysis of a single-center experience.

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Subtotal splenectomy for splenomegaly in cirrhotic patients.

Chu H, Liu X, Zhao J, Xu Y, Wang L, Wang T Int J Clin Exp Pathol. 2014; 7(8):4981-90.

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