Carbapenem-hydrolyzing Class D β-lactamase OXA-48 in Klebsiella Pneumoniae Isolates from Tunisia

Overview

Journal Eur J Clin Microbiol Infect Dis

Publisher Springer

Specialties Infectious Diseases
Microbiology

Date 2011 Sep 15

PMID 21915739

Citations 12

Authors

H Lahlaoui

L Poirel

F Barguellil

M B Moussa

P Nordmann

Affiliations

Soon will be listed here.

Abstract

Two carbapenem-resistant Klebsiella pneumoniae isolates producing the plasmid-encoded carbapenem-hydrolyzing OXA-48 were identified. These isolates, recovered from two patients hospitalized in two different hospitals in Tunisia in December 2010, were not clonally related. Molecular investigations showed that both isolates co-produced the narrow-spectrum β-lactamases TEM-1 and SHV-1, together with the extended-spectrum β-lactamase CTX--15.

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