Vasculitides Throughout History and Their Clinical Treatment Today

Overview

Journal Curr Rheumatol Rep

Publisher Current Science

Specialty Rheumatology

Date 2011 Sep 10

PMID 21904885

Citations 1

Authors

Antonio Iglesias-Gamarra

Edgar Penaranda

Luis R Espinoza

Affiliations

Soon will be listed here.

Abstract

Therapeutic management of the vasculitides is closely linked to modern rheumatologic advances, particularly as it relates to the discovery and first clinical use of glucocorticoids. These compounds were introduced in the late-1940s for the treatment of rheumatoid arthritis, but soon after, clinicians in Europe and the United States realized that they could have a significant positive impact in systemic vasculitides. However, once it was realized that glucocorticoid use was associated with a high degree of morbidity, the search for better immunosuppressive agents with similar efficacy but improved safety profiles was on. During the past several years, several agents have been utilized for the therapeutic management of systemic vasculitides, and the list keeps growing with the development of newer compounds that have retained efficacy but with a better safety profile.

Citing Articles

Treatment goals in ANCA-associated vasculitis: defining success in a new era.

Alberici F, Tedesco M, Popov T, Balcells-Oliver M, Mescia F Front Immunol. 2024; 15:1409129.

PMID: 38938575 PMC: 11208472. DOI: 10.3389/fimmu.2024.1409129.

References

SHICK R, BAGGENSTOSS A, FULLER B, POLLEY H . Effects of cortisone and ACTH on periarteritis nodosa and cranial arteritis. Proc Staff Meet Mayo Clin. 1950; 25(17):492-4. View

Wolff S, Fauci A, Horn R, Dale D . Wegener's granulomatosis. Ann Intern Med. 1974; 81(4):513-25. DOI: 10.7326/0003-4819-81-4-513. View

COOPER B, Bacal E, Patterson R . Allergic angiitis and granulomatosis. Prolonged remission induced by combined prednisone--azathioprine therapy. Arch Intern Med. 1978; 138(3):367-71. DOI: 10.1001/archinte.138.3.367. View

CAPIZZI R, Bertino J . Methotrexate therapy of Wegener's granulomatosis. Ann Intern Med. 1971; 74(1):74-9. DOI: 10.7326/0003-4819-74-1-74. View

Hollander D, Manning R . The use of alkylating agents in the treatment of Wegener's granulomatosis. Ann Intern Med. 1967; 67(2):393-8. DOI: 10.7326/0003-4819-67-2-393. View

Hunder G . The early history of giant cell arteritis and polymyalgia rheumatica: first descriptions to 1970. Mayo Clin Proc. 2006; 81(8):1071-83. DOI: 10.4065/81.8.1071. View

Tannenbaum H . Combined therapy with methotrexate and prednisone in polyarteritis nodosa. Can Med Assoc J. 1980; 123(9):893-4. PMC: 1704906. View

Houssiau F, DCruz D, Haga H, Hughes G . Short course of weekly low-dose intravenous pulse cyclophosphamide in the treatment of lupus nephritis: a preliminary study. Lupus. 1991; 1(1):31-5. DOI: 10.1177/096120339100100106. View

POLLEY H, Slocumb C . Behind the scenes with cortisone and ACTH. Mayo Clin Proc. 1976; 51(8):471-7. View

10.

CHASIS H, GOLDRING W, Baldwin D . Effect of febrile plasma, typhoid vaccine and nitrogen mustard on renal manifestations of human glomerulonephritis. Proc Soc Exp Biol Med. 1949; 71(4):565-7. DOI: 10.3181/00379727-71-17257. View

11.

Butler W, Rossen R . Effects of corticosteroids on immunity in man. I. Decreased serum IgG concentration caused by 3 or 5 days of high doses of methylprednisolone. J Clin Invest. 1973; 52(10):2629-40. PMC: 302523. DOI: 10.1172/JCI107455. View

12.

ALESTIG K, Barr J . Giant-cell arteritis. A biopsy study of polymyalgia rheumatica, including one case of Takayasu's disease. Lancet. 1963; 1(7293):1228-30. DOI: 10.1016/s0140-6736(63)91861-0. View

13.

Jayne D, Rasmussen N, Andrassy K, Bacon P, Cohen Tervaert J, Dadoniene J . A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies. N Engl J Med. 2003; 349(1):36-44. DOI: 10.1056/NEJMoa020286. View

14.

Forestier J, CERTONCINY A . [Rhizomelic pseudo-polarythritis]. Rev Rhum Mal Osteoartic. 1953; 20(12):854-62. View

15.

Elsner B, HARPER F . Disseminated Wegener's granulomatosis with breast involvement. Report of a case. Arch Pathol. 1969; 87(5):544-7. View

16.

Langford C, Talar-Williams C, Barron K, Sneller M . Use of a cyclophosphamide-induction methotrexate-maintenance regimen for the treatment of Wegener's granulomatosis: extended follow-up and rate of relapse. Am J Med. 2003; 114(6):463-9. DOI: 10.1016/s0002-9343(03)00077-9. View

17.

Boyle A, Beatty D . Polymyalgia Rheumatica. Proc R Soc Med. 2009; 54(8):681-4. PMC: 1870384. View

18.

Fauci A, Katz P, Haynes B, Wolff S . Cyclophosphamide therapy of severe systemic necrotizing vasculitis. N Engl J Med. 1979; 301(5):235-8. DOI: 10.1056/NEJM197908023010503. View

19.

Langford C, Sneller M, Hoffman G . Methotrexate use in systemic vasculitis. Rheum Dis Clin North Am. 1997; 23(4):841-53. DOI: 10.1016/s0889-857x(05)70363-x. View

20.

KAPLAN S, HAYSLETT J, Calabresi P . Treatment of advanced Wegener's granulomatosis with azathioprine and duazomycin A. N Engl J Med. 1968; 278(5):239-44. DOI: 10.1056/NEJM196802012780503. View