Macroscopic Liquid Crystal Response to Isolated DNA Helices

Overview

Journal Langmuir

Publisher American Chemical Society

Specialty Chemistry

Date 2011 Sep 8

PMID 21894894

Citations 5

Authors

Stephanie M Malone

Daniel K Schwartz

Affiliations

Soon will be listed here.

Abstract

Nematic liquid crystals (LC) were exposed to isolated DNA molecules extended on a surface that imparted a negligible influence on the LC orientation. Although single-stranded DNA aligned the LC in the extension direction, double-stranded DNA (dsDNA) caused alignment at an oblique angle, providing a characteristic response to the chiral dsDNA helix that was readily observed optically. The intrinsic amplification due to LC orientational correlations enabled a macroscopic visible response to a single molecule of extended dsDNA.

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