Association Between Smoking Cessation and Sexual Health in Men

Overview

Journal BJU Int

Specialty Urology

Date 2011 Sep 3

PMID 21883852

Citations 19

Authors

Christopher B Harte

Cindy M Meston

Affiliations

Soon will be listed here.

Abstract

Objective: To provide the first empirical investigation of the association between smoking cessation and indices of physiological and subjective sexual health in men.

Subjects And Methods: Male smokers, irrespective of erectile dysfunction status, who were motivated to stop smoking ('quitters'), were enrolled in an 8-week smoking cessation programme involving a nicotine transdermal patch treatment and adjunctive counselling. Participants were assessed at baseline (while smoking regularly), at mid-treatment (while using a high-dose nicotine transdermal patch), and at a 4-week post-cessation follow-up. Physiological (circumferential change via penile plethysmography) and subjective sexual arousal indices (continuous self-report), as well as self-reported sexual functioning were assessed at each visit.

Results: Intent-to-treat analyses indicated that, at follow-up, successful quitters (n= 20), compared with those who relapsed (n= 45), showed enhanced erectile tumescence responses, and faster onset to reach maximum subjective sexual arousal. Although successful quitters displayed across-session enhancements in sexual function, they did not show a differential improvement compared with unsuccessful quitters.

Conclusions: Smoking cessation significantly enhances both physiological and self-reported indices of sexual health in long-term male smokers, irrespective of baseline erectile impairment. It is hoped that these results may serve as a novel means to motivate men to stop smoking.

Citing Articles

Oxidative stress affects sperm health and fertility-Time to apply facts learned at the bench to help the patient: Lessons for busy clinicians.

Sengupta P, Pinggera G, Calogero A, Agarwal A Reprod Med Biol. 2024; 23(1):e12598.

PMID: 39224210 PMC: 11366688. DOI: 10.1002/rmb2.12598.

Oxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches.

Pavuluri H, Bakhtiary Z, Panner Selvam M, Hellstrom W Medicina (Kaunas). 2024; 60(6).

PMID: 38929625 PMC: 11205999. DOI: 10.3390/medicina60061008.

Erectile Dysfunction Is a Hallmark of Cardiovascular Disease: Unavoidable Matter of Fact or Opportunity to Improve Men's Health?.

Yannas D, Frizza F, Vignozzi L, Corona G, Maggi M, Rastrelli G J Clin Med. 2021; 10(10).

PMID: 34065601 PMC: 8161068. DOI: 10.3390/jcm10102221.

Practical Approaches to Treat ED in PDE5i Nonresponders.

Cai Z, Song X, Zhang J, Yang B, Li H Aging Dis. 2020; 11(5):1202-1218.

PMID: 33014533 PMC: 7505261. DOI: 10.14336/AD.2019.1028.

Analysis of Sexual Disorders in Men with Infrarenal Abdominal Aortic Aneurysm Treated by Stent-Graft or Prosthesis Implantation-A Pilot Study.

Sznapka M, Brzek A, Ziaja D, Tkocz M, Pawlicki K, Ziaja K Medicina (Kaunas). 2020; 56(4).

PMID: 32326264 PMC: 7230504. DOI: 10.3390/medicina56040191.

References

Saunders J, Aasland O, Babor T, De la Fuente J, Grant M . Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption--II. Addiction. 1993; 88(6):791-804. DOI: 10.1111/j.1360-0443.1993.tb02093.x. View

. Annual smoking-attributable mortality, years of potential life lost, and economic costs--United States, 1995-1999. MMWR Morb Mortal Wkly Rep. 2002; 51(14):300-3. View

Lam T, Abdullah A, Ho L, Yip A, Fan S . Smoking and sexual dysfunction in Chinese males: findings from men's health survey. Int J Impot Res. 2005; 18(4):364-9. DOI: 10.1038/sj.ijir.3901436. View

Guay A, Perez J, Heatley G . Cessation of smoking rapidly decreases erectile dysfunction. Endocr Pract. 2004; 4(1):23-6. DOI: 10.4158/EP.4.1.23. View

WATSON D, Clark L, Tellegen A . Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988; 54(6):1063-70. DOI: 10.1037//0022-3514.54.6.1063. View

Tengs T, Osgood N . The link between smoking and impotence: two decades of evidence. Prev Med. 2001; 32(6):447-52. DOI: 10.1006/pmed.2001.0830. View

Gades N, Nehra A, Jacobson D, McGree M, Girman C, Rhodes T . Association between smoking and erectile dysfunction: a population-based study. Am J Epidemiol. 2005; 161(4):346-51. DOI: 10.1093/aje/kwi052. View

Rellini A, McCall K, Randall P, Meston C . The relationship between women's subjective and physiological sexual arousal. Psychophysiology. 2005; 42(1):116-24. DOI: 10.1111/j.1469-8986.2005.00259.x. View

Murray D, OConnell C, Schmid L, Perry C . The validity of smoking self-reports by adolescents: a reexamination of the bogus pipeline procedure. Addict Behav. 1987; 12(1):7-15. DOI: 10.1016/0306-4603(87)90003-7. View

10.

Mannino D, Klevens R, Flanders W . Cigarette smoking: an independent risk factor for impotence?. Am J Epidemiol. 1994; 140(11):1003-8. DOI: 10.1093/oxfordjournals.aje.a117189. View

11.

Fagerstrom K . The epidemiology of smoking: health consequences and benefits of cessation. Drugs. 2002; 62 Suppl 2:1-9. DOI: 10.2165/00003495-200262002-00001. View

12.

Skinner H . The drug abuse screening test. Addict Behav. 1982; 7(4):363-71. DOI: 10.1016/0306-4603(82)90005-3. View

13.

Feldman H, Johannes C, Derby C, Kleinman K, Mohr B, Araujo A . Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Prev Med. 2000; 30(4):328-38. DOI: 10.1006/pmed.2000.0643. View

14.

Ayta I, McKinlay J, Krane R . The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999; 84(1):50-6. DOI: 10.1046/j.1464-410x.1999.00142.x. View

15.

Rosen R, Riley A, Wagner G, Osterloh I, Kirkpatrick J, Mishra A . The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997; 49(6):822-30. DOI: 10.1016/s0090-4295(97)00238-0. View

16.

Young J, Bennett C, Gilhooly P, Wessells H, Ramos D . Efficacy and safety of sildenafil citrate (Viagra) in black and Hispanic American men. Urology. 2002; 60(2 Suppl 2):39-48. DOI: 10.1016/s0090-4295(02)01689-8. View

17.

Harte C, Meston C . Are the inhibitory effects of nicotine on erectile response in nonsmokers generalizable to long-term smokers? A reply. J Sex Med. 2008; 5(8):2003-4. DOI: 10.1111/j.1743-6109.2008.00891.x. View

18.

Sighinolfi M, Mofferdin A, De Stefani S, Micali S, Cicero A, Bianchi G . Immediate improvement in penile hemodynamics after cessation of smoking: previous results. Urology. 2007; 69(1):163-5. DOI: 10.1016/j.urology.2006.09.026. View

19.

Dorey G . Is smoking a cause of erectile dysfunction? A literature review. Br J Nurs. 2002; 10(7):455-65. DOI: 10.12968/bjon.2001.10.7.5331. View

20.

Heatherton T, Kozlowski L, Frecker R, Fagerstrom K . The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. Br J Addict. 1991; 86(9):1119-27. DOI: 10.1111/j.1360-0443.1991.tb01879.x. View