Spectrin-based Skeleton As an Actor in Cell Signaling

Overview

Journal Cell Mol Life Sci

Publisher Springer

Specialty Biology

Date 2011 Aug 31

PMID 21877118

Citations 60

Authors

B Machnicka

R Grochowalska

D M Boguslawska

A F Sikorski

M C Lecomte

Affiliations

Soon will be listed here.

Abstract

This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the commonly known role of the spectrin-based skeleton in control of membrane organization, stability and shape, and tethering protein mosaics to the cellular motors and to all major filament systems. Particular effort has been undertaken to highlight recent advances linking spectrin to cell signaling phenomena and its participation in signal transduction pathways in many cell types.

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