Clinical Value of Integrated [18F]fluoro-2-deoxy-D-glucose Positron Emission Tomography/computed Tomography in the Preoperative Assessment of Papillary Thyroid Carcinoma: Comparison with Sonography

Overview

Journal J Ultrasound Med

Date 2011 Aug 31

PMID 21876098

Citations 12

Authors

Woo Hee Choi

Yong-An Chung

Eun Ji Han

Hyung Sun Sohn

Sang Hoon Lee

Affiliations

Soon will be listed here.

Abstract

Objectives: The purpose of this study was to evaluate the clinical value of preoperative [(18)F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT) by comparing it to neck sonography in papillary thyroid carcinoma.

Methods: The diagnostic accuracies of PET/CT and sonography for detecting cervical node metastasis were compared. The association between FDG uptake in the primary tumor and the prognostic factors of differentiated thyroid cancer, such as tumor size, multiplicity, extrathyroid extension, and lymph node metastasis, was also assessed.

Results: Positron emission tomography/computed tomography showed lower sensitivity and higher specificity than sonography for detection of cervical node metastasis; however, no statistically significant difference was noted (P > .99). Only the tumor size was associated with FDG uptake in the primary tumor.

Conclusions: [(18)F]Fluoro-2-deoxy-d-glucose PET/CT could not provide additional information compared to neck sonography.

Citing Articles

Role of computed tomography in the evaluation of regional metastasis in well-differentiated thyroid cancer.

Vaish R, Mahajan A, Sable N, Dusane R, Deshmukh A, Bal M Front Radiol. 2023; 3:1243000.

PMID: 38022790 PMC: 10643764. DOI: 10.3389/fradi.2023.1243000.

Diagnostic potential of ultrasonography and computed tomography in differentiating cervical lymph node metastasis of thyroid cancer: a systematic review and meta-analysis.

Chen Y, Zhang Y Arch Med Sci. 2023; 19(4):965-975.

PMID: 37560722 PMC: 10408019. DOI: 10.5114/aoms.2020.95104.

Molecular Imaging and Theragnostics of Thyroid Cancers.

Giovanella L, Deandreis D, Vrachimis A, Campenni A, Petranovic Ovcaricek P Cancers (Basel). 2022; 14(5).

PMID: 35267580 PMC: 8909041. DOI: 10.3390/cancers14051272.

Diagnostic values of F-18 FDG PET or PET/CT, CT, and US for Preoperative Lymph Node Staging in Thyroid Cancer: A Network Meta-Analysis.

Kim K, Shim S, Lee S, Kim S Br J Radiol. 2021; 94(1120):20201076.

PMID: 33595337 PMC: 8010543. DOI: 10.1259/bjr.20201076.

Late recurrence of a papillary thyroid carcinoma 37 years after hemithyroidectomy: Solitary, left cervical lymph node metastasis evident on fluorodeoxyglucose positron-emission tomography/computed tomography images revealing nodular uptake.

Kunogi H, Naoi Y, Matsumoto T, Ozaki Y World J Nucl Med. 2020; 19(2):155-158.

PMID: 32939207 PMC: 7478299. DOI: 10.4103/wjnm.WJNM_72_19.