A Fully Automated Trabecular Bone Structural Analysis Tool Based on T2* -weighted Magnetic Resonance Imaging

Overview

Journal Comput Med Imaging Graph

Specialty Radiology

Date 2011 Aug 25

PMID 21862288

Citations 2

Authors

Markus Kraiger

Petros Martirosian

Peter Opriessnig

Frank Eibofner

Hansjoerg Rempp

Michael Hofer

Fritz Schick

Rudolf Stollberger

Affiliations

Soon will be listed here.

Abstract

One major source affecting the precision of bone structure analysis in quantitative magnetic resonance imaging (qMRI) is inter- and intraoperator variability, inherent in delineating and tracing regions of interest along longitudinal studies. In this paper an automated analysis tool, featuring bone marrow segmentation, region of interest generation, and characterization of cancellous bone of articular joints is presented. In evaluation studies conducted at the knee joint the novel analysis tool significantly decreased the standard error of measurement and improved the sensitivity in detecting minor structural changes. It further eliminated the need of time-consuming user interaction, and thereby increasing reproducibility.

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