Gomari M, Abkhiz S, Pour T, Lotfi E, Rostami N, Nafe Monfared F
Mol Med. 2022; 28(1):146.
PMID: 36476230
PMC: 9730693.
DOI: 10.1186/s10020-022-00577-3.
Haniff H, Liu X, Tong Y, Meyer S, Knerr L, Lemurell M
Cell Chem Biol. 2021; 29(2):300-311.e10.
PMID: 34320373
PMC: 8867599.
DOI: 10.1016/j.chembiol.2021.07.006.
Suresh B, Li W, Zhang P, Wang K, Yildirim I, Parker C
Proc Natl Acad Sci U S A. 2020; 117(52):33197-33203.
PMID: 33318191
PMC: 7777249.
DOI: 10.1073/pnas.2012217117.
Liu X, Haniff H, Childs-Disney J, Shuster A, Aikawa H, Adibekian A
J Am Chem Soc. 2020; 142(15):6970-6982.
PMID: 32233464
PMC: 7357852.
DOI: 10.1021/jacs.9b13159.
Zhang P, Park H, Zhang J, Junn E, Andrews R, Pradeep Velagapudi S
Proc Natl Acad Sci U S A. 2020; 117(3):1457-1467.
PMID: 31900363
PMC: 6983430.
DOI: 10.1073/pnas.1905057117.
A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin.
Costales M, Hoch D, Abegg D, Childs-Disney J, Pradeep Velagapudi S, Adibekian A
J Am Chem Soc. 2019; 141(7):2960-2974.
PMID: 30726072
PMC: 6400281.
DOI: 10.1021/jacs.8b10558.
Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.
Angelbello A, Chen J, Childs-Disney J, Zhang P, Wang Z, Disney M
Chem Rev. 2018; 118(4):1599-1663.
PMID: 29322778
PMC: 5989578.
DOI: 10.1021/acs.chemrev.7b00504.
Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1.
Chen J, VanEtten D, Fountain M, Yildirim I, Disney M
Biochemistry. 2017; 56(27):3463-3474.
PMID: 28617590
PMC: 5810133.
DOI: 10.1021/acs.biochem.7b00252.
Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit.
Costales M, Haga C, Pradeep Velagapudi S, Childs-Disney J, Phinney D, Disney M
J Am Chem Soc. 2017; 139(9):3446-3455.
PMID: 28240549
PMC: 5810126.
DOI: 10.1021/jacs.6b11273.
Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence.
Disney M, Angelbello A
Acc Chem Res. 2016; 49(12):2698-2704.
PMID: 27993012
PMC: 5286924.
DOI: 10.1021/acs.accounts.6b00326.
Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10.
Yang W, Gao R, Southern M, Sarkar P, Disney M
Nat Commun. 2016; 7:11647.
PMID: 27248057
PMC: 4895354.
DOI: 10.1038/ncomms11647.
Design of a small molecule against an oncogenic noncoding RNA.
Pradeep Velagapudi S, Cameron M, Haga C, Rosenberg L, Lafitte M, Duckett D
Proc Natl Acad Sci U S A. 2016; 113(21):5898-903.
PMID: 27170187
PMC: 4889373.
DOI: 10.1073/pnas.1523975113.
A dynamic combinatorial approach for identifying side groups that stabilize DNA-templated supramolecular self-assemblies.
Paolantoni D, Cantel S, Dumy P, Ulrich S
Int J Mol Sci. 2015; 16(2):3609-25.
PMID: 25667976
PMC: 4346916.
DOI: 10.3390/ijms16023609.
MBNL proteins and their target RNAs, interaction and splicing regulation.
Konieczny P, Stepniak-Konieczna E, Sobczak K
Nucleic Acids Res. 2014; 42(17):10873-87.
PMID: 25183524
PMC: 4176163.
DOI: 10.1093/nar/gku767.
Targeting the androgen receptor with steroid conjugates.
Levine P, Garabedian M, Kirshenbaum K
J Med Chem. 2014; 57(20):8224-37.
PMID: 24936953
PMC: 4207530.
DOI: 10.1021/jm500101h.
Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1.
Haghighat Jahromi A, Fu Y, Miller K, Nguyen L, Luu L, Baranger A
J Med Chem. 2013; 56(23):9471-9481.
PMID: 24188018
PMC: 3925341.
DOI: 10.1021/jm400794z.
Investigating the binding mode of an inhibitor of the MBNL1·RNA complex in myotonic dystrophy type 1 (DM1) leads to the unexpected discovery of a DNA-selective binder.
Wong C, Richardson S, Ho Y, Lucas A, Tuccinardi T, Baranger A
Chembiochem. 2012; 13(17):2505-9.
PMID: 23097190
PMC: 3549434.
DOI: 10.1002/cbic.201200602.
Androgen receptor antagonism by divalent ethisterone conjugates in castrate-resistant prostate cancer cells.
Levine P, Lee E, Greenfield A, Bonneau R, Logan S, Garabedian M
ACS Chem Biol. 2012; 7(10):1693-701.
PMID: 22871957
PMC: 3874888.
DOI: 10.1021/cb300332w.
Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts.
Kumar A, Parkesh R, Sznajder L, Childs-Disney J, Sobczak K, Disney M
ACS Chem Biol. 2012; 7(3):496-505.
PMID: 22252896
PMC: 3306454.
DOI: 10.1021/cb200413a.