» Articles » PMID: 21829102

Phosphoproteomics Microarray Screen Reveals Novel Interaction Between MPL and Tensin2: Implications for Biology, Disease and Therapeutics

Overview
Journal Cell Cycle
Specialty Cell Biology
Date 2011 Aug 11
PMID 21829102
Authors
Affiliations
Soon will be listed here.
References
1.
Pikman Y, Lee B, Mercher T, McDowell E, Ebert B, Gozo M . MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med. 2006; 3(7):e270. PMC: 1502153. DOI: 10.1371/journal.pmed.0030270. View

2.
Kaushansky K, Lok S, Holly R, Broudy V, Lin N, BAILEY M . Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature. 1994; 369(6481):568-71. DOI: 10.1038/369568a0. View

3.
Vigon I, Mornon J, Cocault L, Mitjavila M, Tambourin P, Gisselbrecht S . Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proc Natl Acad Sci U S A. 1992; 89(12):5640-4. PMC: 49348. DOI: 10.1073/pnas.89.12.5640. View

4.
Ding J, Komatsu H, Wakita A, Kato-Uranishi M, Ito M, Satoh A . Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood. 2004; 103(11):4198-200. DOI: 10.1182/blood-2003-10-3471. View

5.
Kaushansky K . The molecular mechanisms that control thrombopoiesis. J Clin Invest. 2005; 115(12):3339-47. PMC: 1297257. DOI: 10.1172/JCI26674. View