Does Lipoprotein (a) Level Have a Predictive Value in Restenosis After Coronary Stenting?

Overview

Journal Int J Prev Med

Date 2011 Aug 4

PMID 21811658

Citations 1

Authors

Alireza Khosravi

Masoud Pourmoghaddas

Fereshteh Ziaie

Arezoo Enteshari

Arsalan Khaledifa

Ahmad Bahonar

Affiliations

Soon will be listed here.

Abstract

Objectives: Lipid disorders, lipoproteins, diabetes mellitus, and hypertension are the known risk factors for coronary artery diseases; however, their role is unknown in restenosis after coronary stenting. This study aimed to review the role of these factors, particularly lipoprotein (a) or Lp (a), as a predictive factor for restenosis after coronary stenting with Bare Metal Stent.

Methods: In this study, coronary artery stenting was performed on 170 patients. Follow-up was done using coronary angiography in 128 patients, 6 months after conducting angioplasty. Clinical and biochemical characteristics of the patients were collected as prospective method and were compared between the patients with and without restenosis.

Results: Restenosis was seen in 46 patients (35.9%). Fasting blood glucose level (FBG) in patients with restenosis was significantly higher than patients without restenosis (102.3 ± 39 mg/dl vs. 84.5 ± 28.9 [OR: 1.02, 95% CI: 1.00-1.04]). Lp (a) levels (OR: 0.54, 95% CI: 0.26-1.10) and other biochemical markers and clinical variables had no correlation with restenosis.

Conclusions: Lipoproteins and lipids may not be the underlying cause of restenosis but accurate control of diabetes may improve prognosis after elective coronary stenting.

Citing Articles

Lipoprotein (a) as a Cardiovascular Risk Factor in Controversial Clinical Scenarios: A Narrative Review.

Abdalla H, Mahmoud A, Khedr A, Farina J, Scalia I, Abbas M Int J Mol Sci. 2024; 25(20).

PMID: 39456811 PMC: 11507037. DOI: 10.3390/ijms252011029.

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