Detrimental Effects of Cigarette Smoking on Lower Extremity Wound Healing

Overview

Journal J Foot Surg

Specialty General Surgery

Date 1990 Jan 1

PMID 2181017

Citations 12

Authors

M A Sherwin

C M Gastwirth

Affiliations

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Abstract

The authors review the detrimental effects of cigarette smoke and its constituents to normal physiology. Nicotine and carbon monoxide, principle components of cigarette smoke appear to exert an influence on wound repair by inhibiting epithelization, damaging blood cellular components, and creating a cellular hypoxia. Recommendations for perioperative cessation of smoking by the patient are made.

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