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Age Difference Explains Gender Difference in Cardiac Intervention Rates After Acute Myocardial Infarction

Overview
Journal Healthc Policy
Specialty Public Health
Date 2011 Aug 2
PMID 21804840
Citations 5
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Abstract

Many investigators have reported higher rates of cardiac procedures for males than females after acute myocardial infarction (AMI), suggesting that men are treated more aggressively than women. However, others have reported no significant differences after controlling for age, resulting in uncertainty about the existence of a true gender bias in cardiac care. In this study, a population-based cohort approach was used to calculate age-specific procedure rates by sex from administrative data. Chi-square tests and generalized linear modelling were used to assess gender differences and interactions. For all four procedures studied, rates were significantly higher for males than females (p<0.01). However, age-specific rates revealed few significant differences by gender and a sharp decrease in intervention rates with age for both males and females. Generalized linear modelling confirmed that patient age was a significant predictor of intervention rates, whereas sex was not. The significant gender difference in overall rates was completely confounded by the older age profile of female AMI patients compared to their male counterparts.

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References
1.
Gottlieb S, Harpaz D, Shotan A, Boyko V, Leor J, Cohen M . Sex differences in management and outcome after acute myocardial infarction in the 1990s: A prospective observational community-based study. Israeli Thrombolytic Survey Group. Circulation. 2000; 102(20):2484-90. DOI: 10.1161/01.cir.102.20.2484. View

2.
Harrold L, Esteban J, Lessard D, Yarzebski J, Gurwitz J, Gore J . Narrowing gender differences in procedure use for acute myocardial infarction: insights from the Worcester heart attack study. J Gen Intern Med. 2003; 18(6):423-31. PMC: 1494881. DOI: 10.1046/j.1525-1497.2003.20929.x. View

3.
Moriel M, Behar S, Tzivoni D, Hod H, Boyko V, Gottlieb S . Management and outcomes of elderly women and men with acute coronary syndromes in 2000 and 2002. Arch Intern Med. 2005; 165(13):1521-6. DOI: 10.1001/archinte.165.13.1521. View

4.
Rathore S, Wang Y, Radford M, Ordin D, Krumholz H . Sex differences in cardiac catheterization after acute myocardial infarction: the role of procedure appropriateness. Ann Intern Med. 2002; 137(6):487-93. DOI: 10.7326/0003-4819-137-6-200209170-00008. View

5.
Blomkalns A, Chen A, Hochman J, Peterson E, Trynosky K, Diercks D . Gender disparities in the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: large-scale observations from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early.... J Am Coll Cardiol. 2005; 45(6):832-7. DOI: 10.1016/j.jacc.2004.11.055. View