Gastrointestinal Involvement in Langerhans' Cell Histiocytosis (Histiocytosis X): a Clinical Report of Three Cases

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 1990 Feb 1

PMID 2178934

Citations 6

Authors

R M Egeler

M E Schipper

H S Heymans

Affiliations

Soon will be listed here.

Abstract

The gastrointestinal tract may be involved in Langerhans' cell histiocytosis, either as part of a generalized disease or as a separate primary entity. Three patients with gastrointestinal involvement are described. One patient presented with a history of prolonged vomiting and diarrhoea with blood and mucus. In this case the diagnosis was based on colonic biopsies. Gastrointestinal tract involvement and its investigation in the diagnosis of Langerhans' cell histiocytosis are discussed.

Citing Articles

Successful treatment with 2-chlorodeoxyadenosine of refractory pediatric Langerhans cell histiocytosis with initial involvement of the gastrointestinal tract.

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A rare case of langerhans cell histiocytosis of the gastrointestinal tract.

Shankar U, Prasad M, Chaurasia O World J Gastroenterol. 2012; 18(12):1410-3.

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Intestinal Langerhans cell histiocytosis-like lesion in an adult presented with diverticulitis: a reactive or neoplastic condition?.

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Langerhan's cell histiocytosis complicating small bowel Crohn's disease.

Lee-Elliott C, Alexander J, Gould A, Talbot R, Snook J Gut. 1996; 38(2):296-8.

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Multisystem Langerhans' cell histiocytosis with pancreatic involvement.

Yu R, Attra A, Quinn C, Krausz T, Chu A Gut. 1993; 34(4):570-2.

PMID: 8491411 PMC: 1374325. DOI: 10.1136/gut.34.4.570.

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