Nutrition and Gut Immunity

Overview

Journal Surg Clin North Am

Specialty General Surgery

Date 2011 Jul 27

PMID 21787966

Citations 22

Authors

Kazuhiko Fukatsu

Kenneth A Kudsk

Affiliations

Soon will be listed here.

Abstract

The human intestine contains huge amounts of nonpathologic bacteria surviving in an environment that is beneficial to both the host and the bacterial populations. When short pauses in oral intake occur with minimal alterations in the mucosa-microbial interface, critical illness, with its attendant acidosis, prolonged gastrointestinal tract starvation, exogenous antibiotics, and breakdown in mucosal defenses, renders the host vulnerable to bacterial challenge and also threatens the survival of the bacteria. This review examines the altered innate and adaptive immunologic host defenses that occur as a result of altered oral or enteral intake and/or injury.

Citing Articles

Intestinal Microbiota Dysbiosis Role and Bacterial Translocation as a Factor for Septic Risk.

Charitos I, Scacco S, Cotoia A, Castellaneta F, Castellana G, Pasqualotto F Int J Mol Sci. 2025; 26(5).

PMID: 40076650 PMC: 11900423. DOI: 10.3390/ijms26052028.

Enzymatic Regulation of the Gut Microbiota: Mechanisms and Implications for Host Health.

Jiang Z, Mei L, Li Y, Guo Y, Yang B, Huang Z Biomolecules. 2025; 14(12.

PMID: 39766345 PMC: 11727233. DOI: 10.3390/biom14121638.

Effects of crude protein and non-essential amino acids on growth performance, blood profile, and intestinal health of weaned piglets.

Correia A, Genova J, Saraiva A, Rocha G Front Vet Sci. 2023; 10:1243357.

PMID: 38098993 PMC: 10720428. DOI: 10.3389/fvets.2023.1243357.

Building better barriers: how nutrition and undernutrition impact pediatric intestinal health.

Andres S, Zhang Y, Kuhn M, Scottoline B Front Immunol. 2023; 14:1192936.

PMID: 37545496 PMC: 10401430. DOI: 10.3389/fimmu.2023.1192936.

Nutrition Therapy for Patients With Traumatic Brain Injury: A Narrative Review.

Jeong H, Kim J, Choo Y, Kim M, Lee S, Ha E Korean J Neurotrauma. 2023; 19(2):177-184.

PMID: 37431366 PMC: 10329886. DOI: 10.13004/kjnt.2023.19.e31.

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