Mycobacteria in Terrestrial Small Mammals on Cattle Farms in Tanzania

Overview

Journal Vet Med Int

Publisher Wiley

Specialty Veterinary Medicine

Date 2011 Jul 26

PMID 21785686

Citations 9

Authors

Lies Durnez

Abdul Katakweba

Harrison Sadiki

Charles R Katholi

Rudovick R Kazwala

Robert R Machangu

Francoise Portaels

Herwig Leirs

Affiliations

Soon will be listed here.

Abstract

The control of bovine tuberculosis and atypical mycobacterioses in cattle in developing countries is important but difficult because of the existence of wildlife reservoirs. In cattle farms in Tanzania, mycobacteria were detected in 7.3% of 645 small mammals and in cow's milk. The cattle farms were divided into "reacting" and "nonreacting" farms, based on tuberculin tests, and more mycobacteria were present in insectivores collected in reacting farms as compared to nonreacting farms. More mycobacteria were also present in insectivores as compared to rodents. All mycobacteria detected by culture and PCR in the small mammals were atypical mycobacteria. Analysis of the presence of mycobacteria in relation to the reactor status of the cattle farms does not exclude transmission between small mammals and cattle but indicates that transmission to cattle from another source of infection is more likely. However, because of the high prevalence of mycobacteria in some small mammal species, these infected animals can pose a risk to humans, especially in areas with a high HIV-prevalence as is the case in Tanzania.

Citing Articles

Mycobacterial Interspersed Repeat Unit-Variable Number Tandem Repeat Typing of Strains Isolated from the Lymph Nodes of Free-Living Carnivorous Animals in Poland.

Orlowska B, Majchrzak M, Didkowska A, Anusz K, Krajewska-Wedzina M, Zabost A Pathogens. 2023; 12(9).

PMID: 37764992 PMC: 10536629. DOI: 10.3390/pathogens12091184.

The Presence of in Wild Rodents.

Lima M, Silvestre M, Dos Santos E, Martins L, Quaresma J, de Barros B Microorganisms. 2022; 10(6).

PMID: 35744632 PMC: 9228809. DOI: 10.3390/microorganisms10061114.

Tuberculosis Infection: Occurrence and Risk Factors in Presumptive Tuberculosis Patients of the Serengeti Ecosystem in Tanzania.

Mbugi E, Katale B, Lupindu A, Keyyu J, Kendall S, Dockrell H East Afr Health Res J. 2021; 1(1):19-30.

PMID: 34308155 PMC: 8279301. DOI: 10.24248/EAHRJ-D-16-00319.

Isolation and Histopathological Changes Associated with Non-Tuberculous Mycobacteria in Lymph Nodes Condemned at a Bovine Slaughterhouse.

Hernandez-Jarguin A, Martinez-Burnes J, Molina-Salinas G, de la Cruz-Hernandez N, Palomares-Rangel J, Lopez Mayagoitia A Vet Sci. 2020; 7(4).

PMID: 33182568 PMC: 7712099. DOI: 10.3390/vetsci7040172.

Detection of Wood Mice () Carrying Non-Tuberculous Mycobacteria Able to Infect Cattle and Interfere with the Diagnosis of Bovine Tuberculosis.

Varela-Castro L, Torrontegi O, Sevilla I, Barral M Microorganisms. 2020; 8(3).

PMID: 32155849 PMC: 7143357. DOI: 10.3390/microorganisms8030374.

References

Hendrick S, Kelton D, Leslie K, Lissemore K, Archambault M, Duffield T . Effect of paratuberculosis on culling, milk production, and milk quality in dairy herds. J Am Vet Med Assoc. 2005; 227(8):1302-8. DOI: 10.2460/javma.2005.227.1302. View

Katholi C, Unnasch T . Important experimental parameters for determining infection rates in arthropod vectors using pool screening approaches. Am J Trop Med Hyg. 2006; 74(5):779-85. View

Drewe J, Foote A, Sutcliffe R, Pearce G . Pathology of Mycobacterium bovis infection in wild meerkats (Suricata suricatta). J Comp Pathol. 2008; 140(1):12-24. DOI: 10.1016/j.jcpa.2008.09.004. View

Crump J, van Ingen J, Morrissey A, Boeree M, Mavura D, Swai B . Invasive disease caused by nontuberculous mycobacteria, Tanzania. Emerg Infect Dis. 2009; 15(1):53-5. PMC: 2660713. DOI: 10.3201/eid1501.081093. View

Clarke K, Fitzgerald S, Zwick L, Church S, Kaneene J, Wismer A . Experimental inoculation of meadow voles (Microtus pennsylvanicus), house mice (Mus musculus), and Norway rats (Rattus norvegicus) with Mycobacterium bovis. J Wildl Dis. 2007; 43(3):353-65. DOI: 10.7589/0090-3558-43.3.353. View

Vansteelandt S, Goetghebeur E, Verstraeten T . Regression models for disease prevalence with diagnostic tests on pools of serum samples. Biometrics. 2000; 56(4):1126-33. DOI: 10.1111/j.0006-341x.2000.01126.x. View

Pfaller M . Application of new technology to the detection, identification, and antimicrobial susceptibility testing of mycobacteria. Am J Clin Pathol. 1994; 101(3):329-37. DOI: 10.1093/ajcp/101.3.329. View

Fukushima R, Kawakami S, Iinuma H, Okinaga K . [Molecular diagnosis of infectious disease]. Nihon Geka Gakkai Zasshi. 2003; 104(7):518-22. View

Bercovier H, Vincent V . Mycobacterial infections in domestic and wild animals due to Mycobacterium marinum, M. fortuitum, M. chelonae, M. porcinum, M. farcinogenes, M. smegmatis, M. scrofulaceum, M. xenopi, M. kansasii, M. simiae and M. genavense. Rev Sci Tech. 2001; 20(1):265-90. DOI: 10.20506/rst.20.1.1269. View

10.

Tappe J, Weitzman I, Liu S, Dolensek E, Karp D . Systemic Mycobacterium marinum infection in a European hedgehog. J Am Vet Med Assoc. 1983; 183(11):1280-1. View

11.

WINDSOR R, Durrant D, Burn K . Avian tuberculosis in pigs: Mycobacterium intracellulare infection in a breeding herd. Vet Rec. 1984; 114(20):497-500. DOI: 10.1136/vr.114.20.497. View

12.

Delahay R, Cheeseman C, Clifton-Hadley R . Wildlife disease reservoirs: the epidemiology of Mycobacterium bovis infection in the European badger (Meles meles) and other British mammals. Tuberculosis (Edinb). 2001; 81(1-2):43-9. DOI: 10.1054/tube.2000.0266. View

13.

Portaels F . Proposed minimal standards for the genus Mycobacterium and for description of new slowly growing Mycobacterium species. Int J Syst Bacteriol. 1992; 42(2):315-23. DOI: 10.1099/00207713-42-2-315. View

14.

Thorel M, Huchzermeyer H, Michel A . Mycobacterium avium and Mycobacterium intracellulare infection in mammals. Rev Sci Tech. 2001; 20(1):204-18. DOI: 10.20506/rst.20.1.1272. View

15.

Chiang C, REEVES W . Statistical estimation of virus infection rates in mosquito vector populations. Am J Hyg. 1962; 75:377-91. DOI: 10.1093/oxfordjournals.aje.a120259. View

16.

Mdegela R, Kusiluka L, Kapaga A, Karimuribo E, Turuka F, Bundala A . Prevalence and determinants of mastitis and milk-borne zoonoses in smallholder dairy farming sector in Kibaha and Morogoro districts in Eastern Tanzania. J Vet Med B Infect Dis Vet Public Health. 2004; 51(3):123-8. DOI: 10.1111/j.1439-0450.2004.00735.x. View

17.

Durnez L, Eddyani M, Mgode G, Katakweba A, Katholi C, Machangu R . First detection of mycobacteria in African rodents and insectivores, using stratified pool screening. Appl Environ Microbiol. 2007; 74(3):768-73. PMC: 2227704. DOI: 10.1128/AEM.01193-07. View

18.

Mfinanga S, Morkve O, Kazwala R, Cleaveland S, Sharp M, Kunda J . Mycobacterial adenitis: role of Mycobacterium bovis, non-tuberculous mycobacteria, HIV infection, and risk factors in Arusha, Tanzania. East Afr Med J. 2005; 81(4):171-8. DOI: 10.4314/eamj.v81i4.9150. View

19.

Corner L . The role of wild animal populations in the epidemiology of tuberculosis in domestic animals: how to assess the risk. Vet Microbiol. 2005; 112(2-4):303-12. DOI: 10.1016/j.vetmic.2005.11.015. View

20.

Collins P, MATTHEWS P, McDIARMID A, Brown A . The pathogenicity of Mycobacterium avium and related mycobacteria for experimental animals. J Med Microbiol. 1983; 16(1):27-35. DOI: 10.1099/00222615-16-1-27. View