Recurrent Intravascular-catheter-related Bacteremia Caused by Delftia Acidovorans in a Hemodialysis Patient

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 2011 Jul 22

PMID 21775546

Citations 19

Authors

Kobkul Chotikanatis

Martin Backer

Gabriela Rosas-Garcia

Margaret R Hammerschlag

Affiliations

Soon will be listed here.

Abstract

We report the first case of recurrent intravascular-catheter-related bacteremia in a pediatric hemodialysis patient caused by Delftia acidovorans, previously called Comamonas acidovorans or Pseudomonas acidovorans. The patient had a history of multiple infections of central vascular catheters with other organisms, requiring courses of antibiotics and catheter replacements. Previously reported cases of D. acidovorans infections are reviewed. The isolate appeared to become resistant to cephalosporins after antibiotic treatment, but resistance could not be confirmed with additional testing. In vitro susceptibility testing for cephalosporins is not reliable for this organism.

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References

Woodford N, Fagan E, Ellington M . Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases. J Antimicrob Chemother. 2005; 57(1):154-5. DOI: 10.1093/jac/dki412. View

Stonecipher K, Jensen H, Kastl P, Faulkner A, Rowsey J . Ocular infections associated with Comamonas acidovorans. Am J Ophthalmol. 1991; 112(1):46-9. DOI: 10.1016/s0002-9394(14)76211-7. View

Kawamura I, Yagi T, Hatakeyama K, Ohkura T, Ohkusu K, Takahashi Y . Recurrent vascular catheter-related bacteremia caused by Delftia acidovorans with different antimicrobial susceptibility profiles. J Infect Chemother. 2010; 17(1):111-3. DOI: 10.1007/s10156-010-0089-x. View

Weinstein R, Stamm W, Kramer L, Corey L . Pressure monitoring devices. Overlooked source of nosocomial infection. JAMA. 1976; 236(8):936-8. DOI: 10.1001/jama.236.8.936. View

Franzetti F, Cernuschi M, Esposito R, Moroni M . Pseudomonas infections in patients with AIDS and AIDS-related complex. J Intern Med. 1992; 231(4):437-43. DOI: 10.1111/j.1365-2796.1992.tb00957.x. View

Lair M, Bentolila S, Grenet D, Cahen P, Honderlick P . Oerskovia turbata and Comamonas acidovorans bacteremia in a patient with AIDS. Eur J Clin Microbiol Infect Dis. 1996; 15(5):424-6. DOI: 10.1007/BF01690106. View

Castagnola E, Tasso L, Conte M, Nantron M, Barretta A, Giacchino R . Central venous catheter-related infection due to Comamonas acidovorans in a child with non-Hodgkin's lymphoma. Clin Infect Dis. 1994; 19(3):559-60. DOI: 10.1093/clinids/19.3.559-a. View

Brinser J, Torczynski E . Unusual Pseudomonas corneal ulcers. Am J Ophthalmol. 1977; 84(4):462-6. DOI: 10.1016/0002-9394(77)90435-4. View

Laffineur K, Janssens M, Charlier J, Avesani V, Wauters G, Delmee M . Biochemical and susceptibility tests useful for identification of nonfermenting gram-negative rods. J Clin Microbiol. 2002; 40(3):1085-7. PMC: 120239. DOI: 10.1128/JCM.40.3.1085-1087.2002. View

10.

Lema I, Rodriguez-Ares M . Comamonas acidovorans keratitis in a hydrogel contact lens wearer. CLAO J. 2001; 27(1):55-6. View

11.

Horowitz H, Gilroy S, Feinstein S, Gilardi G . Endocarditis associated with Comamonas acidovorans. J Clin Microbiol. 1990; 28(1):143-5. PMC: 269557. DOI: 10.1128/jcm.28.1.143-145.1990. View

12.

Ender P, Dooley D, Moore R . Vascular catheter-related Comamonas acidovorans bacteremia managed with preservation of the catheter. Pediatr Infect Dis J. 1996; 15(10):918-20. DOI: 10.1097/00006454-199610000-00021. View

13.

Mermel L, Allon M, Bouza E, Craven D, Flynn P, OGrady N . Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2009; 49(1):1-45. PMC: 4039170. DOI: 10.1086/599376. View

14.

Lee S, Kim M, Lee J, Wee W, Lee J . Experience of Comamonas acidovorans keratitis with delayed onset and treatment response in immunocompromised cornea. Korean J Ophthalmol. 2008; 22(1):49-52. PMC: 2629953. DOI: 10.3341/kjo.2008.22.1.49. View

15.

Ravaoarinoro M, Therrien C . Beta-lactamases and outer membrane investigations in beta-lactam-resistant Comamonas acidovorans strains. Int J Antimicrob Agents. 1999; 12(1):27-31. DOI: 10.1016/s0924-8579(98)00095-8. View