ABO-incompatible Kidney Transplantation in Children

Overview

Journal Pediatr Transplant

Specialty Pediatrics

Date 2011 Jul 21

PMID 21771231

Citations 13

Authors

Gunnar Tyden

Gunilla Kumlien

Ulla B Berg

Affiliations

Soon will be listed here.

Abstract

We designed a new protocol to enable safe ABO-incompatible kidney transplantation. The new protocol utilizes antigen-specific immunoadsorption rather than unspecific plasma exchange to remove existing anti A/B antibodies and rituximab rather than splenectomy to prevent rebound of antibodies. Sixty patients have so far been successfully transplanted with this protocol and 10 of those have been children. When compared with ABO-compatible transplantations, we could not find any differences in success rate, renal function, or adverse events.

Citing Articles

A comparative study on outcomes of ABO-incompatible kidney transplants between robot-assisted vs. open surgery-propensity score-matched analysis: a retrospective cohort study.

Kim J, Kwon H, Ko Y, Jung J, Kwon H, Kim Y BMC Nephrol. 2024; 25(1):410.

PMID: 39543527 PMC: 11566057. DOI: 10.1186/s12882-024-03842-1.

Considering ABO Incompatible Living Donor Kidney Transplantation Before Deceased Donor Kidney Transplantation in Children: A Letter to the Editor.

Paessler A, Stojanovic J Transpl Int. 2023; 36:11613.

PMID: 37789915 PMC: 10542673. DOI: 10.3389/ti.2023.11613.

Successful ABO and HLA incompatible kidney transplantation in children in the UK.

Hew E, Kessaris N, Stojanovic J, Jones H, Christian M, Edwards A Pediatr Nephrol. 2022; 38(2):529-535.

PMID: 35695967 PMC: 9763153. DOI: 10.1007/s00467-022-05583-5.

A donor risk index for graft loss in pediatric living donor kidney transplantation.

Wasik H, Pruette C, Ruebner R, McAdams-DeMarco M, Zhou S, Neu A Am J Transplant. 2019; 19(10):2775-2782.

PMID: 30875148 PMC: 6745273. DOI: 10.1111/ajt.15360.

Current progress in ABO-incompatible kidney transplantation.

Koo T, Yang J Kidney Res Clin Pract. 2015; 34(3):170-9.

PMID: 26484043 PMC: 4608875. DOI: 10.1016/j.krcp.2015.08.005.