Primary Care Physicians' Awareness, Experience and Opinions of Direct-to-consumer Genetic Testing

Overview

Journal J Genet Couns

Publisher Wiley

Specialty Genetics

Date 2011 Jul 20

PMID 21769569

Citations 49

Authors

Karen P Powell

Whitney A Cogswell

Carol A Christianson

Gaurav Dave

Amit Verma

Sonja Eubanks

Vincent C Henrich

Affiliations

Soon will be listed here.

Abstract

The purpose of this study was to assess primary care physicians' awareness, experience, opinions and preparedness to answer patients' questions regarding direct-to-consumer (DTC) genetic testing. An anonymous survey was mailed to 2,402 family and internal medicine providers in North Carolina. Of the 382 respondents, 38.7% (n = 148) were aware of and 15% (n = 59) felt prepared to answer questions about DTC genetic tests. Respondents aged 50 or older were more likely to be aware of DTC genetic testing than those less than 40 years old (OR = 2.42). Male providers were more likely to feel prepared to answer questions than female providers (OR = 2.65). Among respondents who reportedly were aware, family practitioners were more likely than internists (OR = 3.30) to think DTC testing was clinically useful, and 18.9% had patients ask questions or bring in test results. The small percent of physicians who were aware of DTC genetic testing or felt prepared to answer questions about it suggests that education of providers will be necessary if testing becomes more widespread.

Citing Articles

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References

Guttmacher A, Jenkins J, Uhlmann W . Genomic medicine: who will practice it? A call to open arms. Am J Med Genet. 2002; 106(3):216-22. DOI: 10.1002/ajmg.10008. View

Caulfield T . The informed gatekeeper?: a commentary on genetic tests, marketing pressure and the role of primary care physicians. Health Law Rev. 2005; 9(3):14-8. View

Evans J, Dale D, Fomous C . Preparing for a consumer-driven genomic age. N Engl J Med. 2010; 363(12):1099-103. DOI: 10.1056/NEJMp1006202. View

Williams-Jones B . Where there's a web, there's a way: commercial genetic testing and the Internet. Community Genet. 2003; 6(1):46-57. DOI: 10.1159/000069538. View

Morren M, Rijken M, Baanders A, Bensing J . Perceived genetic knowledge, attitudes towards genetic testing, and the relationship between these among patients with a chronic disease. Patient Educ Couns. 2006; 65(2):197-204. DOI: 10.1016/j.pec.2006.07.005. View

Kolor K, Liu T, St Pierre J, Khoury M . Health care provider and consumer awareness, perceptions, and use of direct-to-consumer personal genomic tests, United States, 2008. Genet Med. 2009; 11(8):595. DOI: 10.1097/GIM.0b013e3181b1cc2c. View

Ohata T, Tsuchiya A, Watanabe M, Sumida T, Takada F . Physicians' opinion for 'new' genetic testing in Japan. J Hum Genet. 2009; 54(4):203-8. DOI: 10.1038/jhg.2009.11. View

Greendale K, Pyeritz R . Empowering primary care health professionals in medical genetics: how soon? How fast? How far?. Am J Med Genet. 2002; 106(3):223-32. DOI: 10.1002/ajmg.10010. View

Burke W . Genetic testing in primary care. Annu Rev Genomics Hum Genet. 2004; 5:1-14. DOI: 10.1146/annurev.genom.5.061903.180029. View

10.

Evans J, Green R . Direct to consumer genetic testing: Avoiding a culture war. Genet Med. 2009; 11(8):568-9. PMC: 2920210. DOI: 10.1097/GIM.0b013e3181afbaed. View

11.

Suther S, Goodson P . Barriers to the provision of genetic services by primary care physicians: a systematic review of the literature. Genet Med. 2003; 5(2):70-6. DOI: 10.1097/01.GIM.0000055201.16487.61. View

12.

Offit K . Genomic profiles for disease risk: predictive or premature?. JAMA. 2008; 299(11):1353-5. DOI: 10.1001/jama.299.11.1353. View

13.

McAvoy B, Kaner E . General practice postal surveys: a questionnaire too far?. BMJ. 1996; 313(7059):732-3; discussion 733-4. PMC: 2352115. DOI: 10.1136/bmj.313.7059.732. View

14.

Gollust S, Wilfond B, Hull S . Direct-to-consumer sales of genetic services on the Internet. Genet Med. 2003; 5(4):332-7. PMC: 4822819. DOI: 10.1097/01.GIM.0000076972.83711.48. View

15.

Wright C, Gregory-Jones S . Size of the direct-to-consumer genomic testing market. Genet Med. 2010; 12(9):594. DOI: 10.1097/GIM.0b013e3181ead743. View

16.

Lind D, Rekkas S, Bui V, Lam T, Beierle E, Copeland 3rd E . Competency-based student self-assessment on a surgery rotation. J Surg Res. 2002; 105(1):31-4. DOI: 10.1006/jsre.2002.6442. View

17.

McGuire A, Diaz C, Wang T, Hilsenbeck S . Social networkers' attitudes toward direct-to-consumer personal genome testing. Am J Bioeth. 2009; 9(6-7):3-10. PMC: 2792120. DOI: 10.1080/15265160902928209. View

18.

Swan M . Multigenic condition risk assessment in direct-to-consumer genomic services. Genet Med. 2010; 12(5):279-88. DOI: 10.1097/GIM.0b013e3181d5f73b. View

19.

Billings P, Kohn M, de Cuevas M, Beckwith J, Alper J, Natowicz M . Discrimination as a consequence of genetic testing. Am J Hum Genet. 1992; 50(3):476-82. PMC: 1684266. View

20.

Miller F, Carroll J, Wilson B, Bytautas J, Allanson J, Cappelli M . The primary care physician role in cancer genetics: a qualitative study of patient experience. Fam Pract. 2010; 27(5):563-9. DOI: 10.1093/fampra/cmq035. View