Multiple Sclerosis and Chronic Cerebrospinal Venous Insufficiency: a Critical Review

Overview

Journal Ther Adv Neurol Disord

Specialty Neurology

Date 2011 Jul 19

PMID 21765873

Citations 2

Authors

Amer M Awad

Ellen Marder

Ron Milo

Olaf Stuve

Affiliations

Soon will be listed here.

Abstract

Chronic cerebrospinal venous insufficiency (CCSVI) was recently proposed as a contributing factor in the pathology of multiple sclerosis. This concept has gained remarkable attention, partly because endovascular neurointervention has been suggested as a treatment strategy. This review summarizes available evidence and provides a critical analysis of the published data. Currently, there is inconclusive evidence to support CCSVI as an etiological factor in patients with multiple sclerosis. Endovascular procedures should not be undertaken outside of controlled clinical trials.

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