Active Transport of Proteins into the Nucleus

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1990 Nov 26

PMID 2175710

Citations 7

Authors

P Wagner

J Kunz

A Koller

M N Hall

Affiliations

Soon will be listed here.

Abstract

Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is a highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.

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