» Articles » PMID: 21749774

Hepatitis E Virus Seroprevalence and Chronic Infections in Patients with HIV, Switzerland

Abstract

We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation.

Citing Articles

Testing Hepatitis E Seroprevalence among HIV-Infected Patients in Greece: The SHIP Study.

Antonopoulou N, Schinas G, Kotsiri Z, Tsachouridou O, Protopapas K, Petrakis V Pathogens. 2024; 13(7).

PMID: 39057763 PMC: 11280285. DOI: 10.3390/pathogens13070536.


Hepatitis E Virus (HEV) Infection Among Immunocompromised Individuals: A Brief Narrative Review.

Alexandrova R, Tsachev I, Kirov P, Abudalleh A, Hristov H, Zhivkova T Infect Drug Resist. 2024; 17:1021-1040.

PMID: 38505248 PMC: 10948336. DOI: 10.2147/IDR.S449221.


Higher Risk of Chronic Hepatitis E Virus Infection in Patients with Human Immunodeficiency Virus-1: An Iranian Cross-sectional Study.

Zahedi M, Shafieipour S, Hayatbakhsh Abassi M, Pourjamali N, Nakhaie M, Charostad J Iran J Pathol. 2023; 18(2):125-133.

PMID: 37600571 PMC: 10439753. DOI: 10.30699/IJP.2023.551657.2870.


Quantification of host proteomic responses to genotype 4 hepatitis E virus replication facilitated by pregnancy serum.

Qian Z, Cong C, Li Y, Bi Y, He Q, Li T Virol J. 2023; 20(1):111.

PMID: 37264422 PMC: 10233519. DOI: 10.1186/s12985-023-02080-5.


Clinical Manifestations of Hepatitis E.

You S, Zhu B, Xin S Adv Exp Med Biol. 2023; 1417:185-197.

PMID: 37223867 DOI: 10.1007/978-981-99-1304-6_13.


References
1.
Colson P, Kaba M, Moreau J, Brouqui P . Hepatitis E in an HIV-infected patient. J Clin Virol. 2009; 45(4):269-71. DOI: 10.1016/j.jcv.2009.06.002. View

2.
Thoden J, Venhoff N, Miehle N, Klar M, Huzly D, Panther E . Hepatitis E and jaundice in an HIV-positive pregnant woman. AIDS. 2008; 22(7):909-10. DOI: 10.1097/QAD.0b013e3282f7cb9a. View

3.
Dalton H, Bendall R, Keane F, Tedder R, Ijaz S . Persistent carriage of hepatitis E virus in patients with HIV infection. N Engl J Med. 2009; 361(10):1025-7. DOI: 10.1056/NEJMc0903778. View

4.
Curry J, Adams N, Crum-Cianflone N . Acute hepatitis E virus infection in an HIV-infected person in the United States. Ann Intern Med. 2009; 150(3):226-7. PMC: 2720044. DOI: 10.7326/0003-4819-150-3-200902030-00028. View

5.
Bendall R, Ellis V, Ijaz S, Ali R, Dalton H . A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries. J Med Virol. 2010; 82(5):799-805. DOI: 10.1002/jmv.21656. View