Ibutilide for the Cardioversion of Paroxysmal Atrial Fibrillation During Radiofrequency Ablation of Supraventricular Tachycardias

Overview

Journal Cardiol Res Pract

Publisher Wiley

Specialty Cardiology & Vascular Diseases

Date 2011 Jul 9

PMID 21738857

Authors

Kostas Polymeropoulos

Vassilios P Vassilikos

Lilian Mantziari

Stelios Paraskevaidis

Theodoros D Karamitsos

Sotirios Mochlas

Georgios Parcharidis

Georgios Louridas

Ioannis H Styliadis

Affiliations

Soon will be listed here.

Abstract

Direct current electrical cardioversion (DC-ECV) is the preferred treatment for the termination of paroxysmal atrial fibrillation (AF) that occurs during radiofrequency ablation (RFA) of supraventricular tachycardias (SVT). Intravenous Ibutilide may be an alternative option in this setting. Thirty-four out of 386 patients who underwent SVT-RFA presented paroxysmal AF during the procedure and were randomized into receiving ibutilide or DC-ECV. Ibutilide infusion successfully cardioverted 16 out of 17 patients (94%) within 17.37 ± 7.87 min. DC-ECV was successful in all patients (100%) within 17.29 ± 3.04 min. Efficacy and total time to cardioversion did not differ between the study groups. No adverse events were observed. RFA was successfully performed in 16 patients (94%) in the ibutilide arm and in all patients (100%) in the DC-ECV arm, p = NS. In conclusion, ibutilide is a safe and effective alternative treatment for restoring sinus rhythm in cases of paroxysmal AF complicating SVT-RFA.

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