Evolution: Structural and Functional Diversity of Cadherin at the Adherens Junction

Overview

Journal J Cell Biol

Specialty Cell Biology

Date 2011 Jun 29

PMID 21708975

Citations 96

Authors

Hiroki Oda

Masatoshi Takeichi

Affiliations

Soon will be listed here.

Abstract

Adhesion between cells is essential to the evolution of multicellularity. Indeed, morphogenesis in animals requires firm but flexible intercellular adhesions that are mediated by subcellular structures like the adherens junction (AJ). A key component of AJs is classical cadherins, a group of transmembrane proteins that maintain dynamic cell-cell associations in many animal species. An evolutionary reconstruction of cadherin structure and function provides a comprehensive framework with which to appreciate the diversity of morphogenetic mechanisms in animals.

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References

Tepass U, Haag T, Omatyar L, Torok T, Hartenstein V . shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphogenetically active epithelia. Genes Dev. 1996; 10(6):672-85. DOI: 10.1101/gad.10.6.672. View

Kazmierczak P, Sakaguchi H, Tokita J, Wilson-Kubalek E, Milligan R, Muller U . Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature. 2007; 449(7158):87-91. DOI: 10.1038/nature06091. View

Ma D, Yang C, McNeill H, Simon M, Axelrod J . Fidelity in planar cell polarity signalling. Nature. 2003; 421(6922):543-7. DOI: 10.1038/nature01366. View

Wong E, Brar S, Sesaki H, Yang C, Siu C . Molecular cloning and characterization of DdCAD-1, a Ca2+-dependent cell-cell adhesion molecule, in Dictyostelium discoideum. J Biol Chem. 1996; 271(27):16399-408. DOI: 10.1074/jbc.271.27.16399. View

Ting C, Yonekura S, Chung P, Hsu S, Robertson H, Chiba A . Drosophila N-cadherin functions in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents. Development. 2005; 132(5):953-63. DOI: 10.1242/dev.01661. View

Ereskovsky A, Borchiellini C, Gazave E, Ivanisevic J, Lapebie P, Perez T . The Homoscleromorph sponge Oscarella lobularis, a promising sponge model in evolutionary and developmental biology: model sponge Oscarella lobularis. Bioessays. 2009; 31(1):89-97. DOI: 10.1002/bies.080058. View

Reddy B, Irvine K . The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development. 2008; 135(17):2827-38. DOI: 10.1242/dev.020974. View

Harrison O, Bahna F, Katsamba P, Jin X, Brasch J, Vendome J . Two-step adhesive binding by classical cadherins. Nat Struct Mol Biol. 2010; 17(3):348-57. PMC: 2872554. DOI: 10.1038/nsmb.1784. View

Yasuda S, Tanaka H, Sugiura H, Okamura K, Sakaguchi T, Tran U . Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases. Neuron. 2007; 56(3):456-71. PMC: 2424284. DOI: 10.1016/j.neuron.2007.08.020. View

10.

Lin Z, Sriskanthadevan S, Huang H, Siu C, Yang D . Solution structures of the adhesion molecule DdCAD-1 reveal new insights into Ca(2+)-dependent cell-cell adhesion. Nat Struct Mol Biol. 2006; 13(11):1016-22. DOI: 10.1038/nsmb1162. View

11.

Katsamba P, Carroll K, Ahlsen G, Bahna F, Vendome J, Posy S . Linking molecular affinity and cellular specificity in cadherin-mediated adhesion. Proc Natl Acad Sci U S A. 2009; 106(28):11594-9. PMC: 2710653. DOI: 10.1073/pnas.0905349106. View

12.

Magie C, Martindale M . Cell-cell adhesion in the cnidaria: insights into the evolution of tissue morphogenesis. Biol Bull. 2008; 214(3):218-32. DOI: 10.2307/25470665. View

13.

Matakatsu H, Blair S . Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development. 2004; 131(15):3785-94. DOI: 10.1242/dev.01254. View

14.

Sesaki H, Wong E, Siu C . The cell adhesion molecule DdCAD-1 in Dictyostelium is targeted to the cell surface by a nonclassical transport pathway involving contractile vacuoles. J Cell Biol. 1997; 138(4):939-51. PMC: 2138044. DOI: 10.1083/jcb.138.4.939. View

15.

Prakash S, Caldwell J, Eberl D, Clandinin T . Drosophila N-cadherin mediates an attractive interaction between photoreceptor axons and their targets. Nat Neurosci. 2005; 8(4):443-50. PMC: 2367251. DOI: 10.1038/nn1415. View

16.

Takeichi M . The cadherin superfamily in neuronal connections and interactions. Nat Rev Neurosci. 2006; 8(1):11-20. DOI: 10.1038/nrn2043. View

17.

Haruta T, Warrior R, Yonemura S, Oda H . The proximal half of the Drosophila E-cadherin extracellular region is dispensable for many cadherin-dependent events but required for ventral furrow formation. Genes Cells. 2010; 15(3):193-208. DOI: 10.1111/j.1365-2443.2010.01389.x. View

18.

Uemura T, Oda H, Kraut R, Hayashi S, Kotaoka Y, Takeichi M . Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo. Genes Dev. 1996; 10(6):659-71. DOI: 10.1101/gad.10.6.659. View

19.

Chapman J, Kirkness E, Simakov O, Hampson S, Mitros T, Weinmaier T . The dynamic genome of Hydra. Nature. 2010; 464(7288):592-6. PMC: 4479502. DOI: 10.1038/nature08830. View

20.

Takeichi M . Morphogenetic roles of classic cadherins. Curr Opin Cell Biol. 1995; 7(5):619-27. DOI: 10.1016/0955-0674(95)80102-2. View