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Management of Exposed, Infected Implant-based Breast Reconstruction and Strategies for Salvage

Overview
Publisher Elsevier
Specialty General Surgery
Date 2011 Jun 29
PMID 21708490
Citations 16
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Abstract

Introduction: Complications of implant-based breast reconstruction are rare but mastectomy flap necrosis and peri-implant infection are the most frequent and remain an important cause of early implant failure. This study aimed to compare the results of three different management strategies employed to deal with these complications at our institution.

Patients And Methods: A consecutive series of 71 infected/exposed prostheses in 68 patients over a 20-year period were analysed. Management strategies included explantation and delayed reconstruction, implant salvage and explantation and immediate autologous reconstruction.

Results: Only 19 of 45 (42%), managed with implant removal, went on to delayed reconstruction. Methods of delayed reconstruction were distributed equally between implant-only, implant and autologous tissue and autologous-only reconstructions. The implant was successfully salvaged in nine cases, but reducing the implant size or introducing new tissue as a flap increased the success from 45% to 53%. Three patients with infected implant-only breast reconstruction underwent explantation and immediate conversion to autologous-only reconstructions.

Conclusions: All the three interventions reviewed here have their place in the management of infected implant-based breast reconstructions. It is noteworthy that following implant removal, the likelihood of the patient proceeding to delayed reconstruction of any kind is similar to the likelihood of successful salvage (42% vs. 45%). This study population had high numbers of exposed implants in irradiated fields. Reducing implant size or introducing new tissue in the form of a flap increases the chances of successful implant salvage. In the presence of mild infection, removal of exposed/infected implants and immediate conversion to an autologous-only reconstruction can prove to be successful.

Citing Articles

Monitoring and Management of Infection following Prepectoral Implant-based Breast Reconstruction: Retrospective Analysis of Conservative Treatment Versus Implant Removal.

Walz S, Martineau J, Kalbermatten D, Oranges C Plast Reconstr Surg Glob Open. 2025; 13(2):e6516.

PMID: 39911536 PMC: 11798385. DOI: 10.1097/GOX.0000000000006516.


Implant-based Breast Reconstruction Salvage with Negative Pressure Wound Therapy with Instillation: An Evaluation of Outcomes.

Ahmed S, Hulsman L, Imeokparia F, Ludwig K, Fisher C, Bamba R Plast Reconstr Surg Glob Open. 2024; 12(9):e6116.

PMID: 39228420 PMC: 11368219. DOI: 10.1097/GOX.0000000000006116.


A Multi-Center Retrospective Observational Analysis of Three-Year Experience of Our Protocol for Prevention and Monitoring of Surgical Site Infections in Implant-Based Breast Reconstruction.

Bottosso S, Sidoti G, Vita L, Scian A, Bonat Guarini L, Renzi N Cancers (Basel). 2024; 16(13).

PMID: 39001499 PMC: 11240831. DOI: 10.3390/cancers16132439.


Alpha Defensin-1 Level Correlates with Periprosthetic Infection Severity following Implant-based Breast Reconstruction.

Sobti N, Vishwanath N, Stead T, Rao V, Soliman L, Breuing K Plast Reconstr Surg Glob Open. 2024; 12(1):e5543.

PMID: 38264447 PMC: 10805421. DOI: 10.1097/GOX.0000000000005543.


A Simple Technique Using Peri-Prosthetic Irrigation Improves Implant Salvage Rates in Immediate Implant-Based Breast Reconstruction.

Gowda M, Jafferbhoy S, Marla S, Narayanan S, Soumian S Medicina (Kaunas). 2023; 59(11).

PMID: 38004088 PMC: 10673091. DOI: 10.3390/medicina59112039.