Phylogenetic Analysis of Porcine Parvoviruses from Swine Samples in China

Overview

Journal Virol J

Publisher Biomed Central

Specialty Microbiology

Date 2011 Jun 28

PMID 21703005

Citations 8

Authors

Xiaofang Hao

Zengjun Lu

Pu Sun

Yuanfang Fu

Yimei Cao

Pinghua Li

Xingwen Bai

Huifang Bao

Baoxia Xie

Yingli Chen

Dong Li

Zaixin Liu

Affiliations

Soon will be listed here.

Abstract

Background: Porcine parvovirus (PPV) usually causes reproductive failure in sows. The objective of the present study was to analyze the phylogenetic distribution and perform molecular characterization of PPVs isolated in China, as well as to identify two field strains, LZ and JY. The data used in this study contained the available sequences for NS1 and VP2 from GenBank, as well as the two aforementioned Chinese strains.

Results: Phylogenetic analysis shows that the PPV sequences are divided into four groups. The early Chinese PPV isolates are Group I viruses, and nearly all of the later Chinese PPV isolates are Group II viruses. LZ belongs to group II, whereas the JY strain is a Group III virus. This is the first report on the isolation of a Group III virus in China. The detection of selective pressures on the PPV genome shows that the NS1 and VP2 genes are under purifying selection and positive selection, respectively. Moreover, the amino acids in the VP2 capsid are highly variable because of the positive selection.

Conclusions: Our study provides new molecular data on PPV strains in China, and emphasizes the importance of etiological studies of PPV in pigs.

Citing Articles

Positivity Status and Molecular Characterization of Porcine Parvoviruses 1 Through 8 (PPV1-PPV8) from Slaughtered Pigs in China.

Zhao D, Lin H, Huang Z, Zhou Y, Qi W, Cui M Animals (Basel). 2024; 14(22).

PMID: 39595291 PMC: 11591526. DOI: 10.3390/ani14223238.

Isolation, characterization, and phylogenetic analysis of two new porcine parvovirus 1 isolates from Northern China.

Deng H, Cong G, Wang H, Hu Z, Shi D, Shi H Virus Res. 2023; 339:199247.

PMID: 37923168 PMC: 10751695. DOI: 10.1016/j.virusres.2023.199247.

Seroprevalence and Risk Factors Investigations of Parvovirus Disease in Tibetan Pigs: First Report from Tibet.

Yan F, Xu S, Chang Z, Nazar M, Chamba Y, Shang P Vet Sci. 2022; 9(10).

PMID: 36288189 PMC: 9610086. DOI: 10.3390/vetsci9100576.

A Systematic Investigation Unveils High Coinfection Status of Porcine Parvovirus Types 1 through 7 in China from 2016 to 2020.

Li J, Xiao Y, Qiu M, Li X, Li S, Lin H Microbiol Spectr. 2021; 9(3):e0129421.

PMID: 34851175 PMC: 8635132. DOI: 10.1128/Spectrum.01294-21.

Two novel protein chips for the detection of antibodies against porcine parvovirus.

Wu Y, Wu X, Hou J, Chen X, Huang X, Zhou B BMC Vet Res. 2020; 16(1):57.

PMID: 32059673 PMC: 7023685. DOI: 10.1186/s12917-020-02280-z.

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