Increased Prevalence of Celiac Disease in Patients with Unexplained Infertility in the United States
Overview
Reproductive Medicine
Authors
Affiliations
Objective: To determine whether there might be an increased prevalence of undiagnosed celiac disease among a population of infertile women using serologic screening.
Study Design: A prospective cohort study was performed at an academic infertility clinic in the United States.
Results: The overall prevalence of celiac disease in this population was 2.1% (4/188). There was a significantly increased prevalence (5.9%) of undiagnosed celiac disease among women presenting with unexplained infertility (n = 51).
Conclusion: Women with unexplained infertility are at increased risk for having undiagnosed celiac disease, which may be a potentially modifiable (and treatable) risk factor.
Celiac Disease: A Forty-Year Analysis in an Italian Referral Center.
Lungaro L, Costanzini A, Manza F, Caputo F, Remelli F, Volpato S Nutrients. 2024; 16(14).
PMID: 39064734 PMC: 11279732. DOI: 10.3390/nu16142292.
Diagnostic accuracy of anti-DGP (IgG) for celiac disease.
Jafari S, Alami A, Sedghi N, Kianifar H, Kiani M, Khalesi M J Family Med Prim Care. 2023; 12(1):42-46.
PMID: 37025242 PMC: 10071923. DOI: 10.4103/jfmpc.jfmpc_326_22.
Triggianese P, Perricone C, De Martino E, DAntonio A, Chimenti M, Conigliaro P Nutrients. 2021; 13(9).
PMID: 34579148 PMC: 8471830. DOI: 10.3390/nu13093270.
The prevalence of celiac disease in women with infertility-A systematic review with meta-analysis.
Glimberg I, Haggard L, Lebwohl B, Green P, Ludvigsson J Reprod Med Biol. 2021; 20(2):224-233.
PMID: 33850456 PMC: 8022102. DOI: 10.1002/rmb2.12374.
Martinez-Rodriguez A, Loaiza-Martinez D, Sanchez-Sanchez J, Marcos-Pardo P, Prats S, Alacid F Int J Environ Res Public Health. 2020; 17(2).
PMID: 31952137 PMC: 7014319. DOI: 10.3390/ijerph17020539.