» Articles » PMID: 21656030

Elderly with Autism: Executive Functions and Memory

Overview
Publisher Springer
Date 2011 Jun 10
PMID 21656030
Citations 46
Authors
Affiliations
Soon will be listed here.
Abstract

Cognitive autism research is mainly focusing on children and young adults even though we know that autism is a life-long disorder and that healthy aging already has a strong impact on cognitive functioning. We compared the neuropsychological profile of 23 individuals with autism and 23 healthy controls (age range 51-83 years). Deficits were observed in attention, working memory, and fluency. Aging had a smaller impact on fluency in the high functioning autism (HFA) group than in the control group, while aging had a more profound effect on visual memory performance in the HFA group. Hence, we provide novel evidence that elderly with HFA have subtle neuropsychological deficits and that the developmental trajectories differ between elderly with and without HFA in particular cognitive domains.

Citing Articles

Transcallosal white matter and cortical gray matter variations in autistic adults aged 30-73 years.

Shin Y, Christensen D, Wang J, Shirley D, Orlando A, Romero R Mol Autism. 2025; 16(1):16.

PMID: 40050930 PMC: 11884179. DOI: 10.1186/s13229-025-00652-6.


Sensory seeking and its influence on sustained attention performance in adult males with Autism Spectrum Condition.

Itahashi T, Aoki R, Nakamura M, Ohta H, Hashimoto R Sci Rep. 2025; 15(1):4047.

PMID: 39901051 PMC: 11790954. DOI: 10.1038/s41598-025-88733-7.


Cognitive and brain morphological deviations in middle-to-old aged autistic adults: A systematic review and meta-analysis.

Wang J, Christensen D, Coombes S, Wang Z Neurosci Biobehav Rev. 2024; 163:105782.

PMID: 38944227 PMC: 11283673. DOI: 10.1016/j.neubiorev.2024.105782.


Aging Well and Autism: A Narrative Review and Recommendations for Future Research.

Klein C, Klinger L Healthcare (Basel). 2024; 12(12).

PMID: 38921321 PMC: 11203987. DOI: 10.3390/healthcare12121207.


Giftedness and atypical sexual differentiation: enhanced perceptual functioning through estrogen deficiency instead of androgen excess.

Sakaguchi K, Tawata S Front Endocrinol (Lausanne). 2024; 15:1343759.

PMID: 38752176 PMC: 11094242. DOI: 10.3389/fendo.2024.1343759.


References
1.
Gilbert S, Bird G, Brindley R, Frith C, Burgess P . Atypical recruitment of medial prefrontal cortex in autism spectrum disorders: an fMRI study of two executive function tasks. Neuropsychologia. 2008; 46(9):2281-91. PMC: 2648877. DOI: 10.1016/j.neuropsychologia.2008.03.025. View

2.
Thakkar K, Polli F, Joseph R, Tuch D, Hadjikhani N, Barton J . Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD). Brain. 2008; 131(Pt 9):2464-78. PMC: 2525446. DOI: 10.1093/brain/awn099. View

3.
Rapin I, Tuchman R . Autism: definition, neurobiology, screening, diagnosis. Pediatr Clin North Am. 2008; 55(5):1129-46, viii. DOI: 10.1016/j.pcl.2008.07.005. View

4.
Pellicano E, Maybery M, Durkin K, Maley A . Multiple cognitive capabilities/deficits in children with an autism spectrum disorder: "weak" central coherence and its relationship to theory of mind and executive control. Dev Psychopathol. 2006; 18(1):77-98. DOI: 10.1017/S0954579406060056. View

5.
Spek A, Scholte E, van Berckelaer-Onnes I . Brief report: The use of WAIS-III in adults with HFA and Asperger syndrome. J Autism Dev Disord. 2007; 38(4):782-7. PMC: 2268726. DOI: 10.1007/s10803-007-0446-5. View