MS Analysis of Nucleic Acids in the Post-genomic Era

Overview

Journal Anal Chem

Specialty Chemistry

Date 2011 Jun 10

PMID 21651236

Citations 7

Authors

D Fabris

Affiliations

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Abstract

Alternative approaches complementing the existing technologies for analysis of nucleic acids and their assemblies are necessary to take on the new challenges posed by the postgenomic era. The versatility of MS in biopolymer analysis and its ability to reach beyond sequence information are the basis of ever expanding applications aimed at the elucidation of nucleic acid structure-function relationships. This Feature summarizes the current state of MS-based approaches devised to overcome the limitations of traditional techniques and to advance different facets of nucleic acids research.

Citing Articles

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Bifunctional cross-linking approaches for mass spectrometry-based investigation of nucleic acids and protein-nucleic acid assemblies.

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