Immune Thrombocytopenia: No Longer 'idiopathic'

Overview

Journal Cleve Clin J Med

Specialty General Medicine

Date 2011 Jun 3

PMID 21632906

Citations 28

Authors

Keith McCrae

Affiliations

Soon will be listed here.

Abstract

Immune thrombocytopenia (ITP) is a common hematologic disorder. Its pathogenesis involves both accelerated platelet destruction and impaired platelet production. First-line agents are usually effective initially but do not provide long-term responses. Splenectomy remains an effective long-term therapy, as does rituximab (Rituxan) in a subset of patients. Thrombopoietic agents offer a new alternative, although their place in the overall management of ITP remains uncertain.

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