Turing's Next Steps: the Mechanochemical Basis of Morphogenesis

Overview

Journal Nat Rev Mol Cell Biol

Specialties Cell Biology
Molecular Biology

Date 2011 May 24

PMID 21602907

Citations 86

Authors

Jonathon Howard

Stephan W Grill

Justin S Bois

Affiliations

Soon will be listed here.

Abstract

Nearly 60 years ago, Alan Turing showed theoretically how two chemical species, termed morphogens, diffusing and reacting with each other can generate spatial patterns. Diffusion plays a crucial part in transporting chemical signals through space to establish the length scale of the pattern. When coupled to chemical reactions, mechanical processes - forces and flows generated by motor proteins - can also define length scales and provide a mechanochemical basis for morphogenesis. forces and flows generated by motor proteins - can also define length scales and provide a mechanochemical basis for morphogenesis.

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